Testing Stents and Alvimopan During Bladder Removal Surgery
Compares ureteral stents and alvimopan in adults having bladder cancer surgery.
Plain-language title generated from the registry record
Registry title: A Study of Surgical Techniques During Cystectomy
Key facts
- Where
- Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, and Rockville Centre, United StatesSee the 7 sites
- Phase
- Phase 3
Where in United States
- Memorial Sloan Kettering at Basking Ridge (Consent Only)Basking Ridge, United StatesTaking people
- Memorial Sloan Kettering Suffolk - Commack (Consent Only)Commack, United StatesTaking people
- Memorial Sloan Kettering Westchester (Consent only)Harrison, United StatesTaking people
- Memorial Sloan Kettering Monmouth (Consent Only)Middletown, United StatesTaking people
- Memorial Sloan Kettering Bergen (Consent Only)Montvale, United StatesTaking people
- Memorial Sloan Kettering Cancer Center (All Protocol Activites)New York, United StatesTaking people
- Memorial Sloan Kettering Nassau (Consent Only)Rockville Centre, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Memorial Sloan Kettering Cancer Center
- Trial code
- NCT06703476
- Record updated
- 22 September 2026
- Original description
The purpose of this study is to look at two standard surgical techniques used during a radical cystectomy and see whether they influence outcomes such as length of stay in the hospital and infections after surgery. This trial will evaluate whether the following surgical methods influence outcomes:Read full original descriptionShow less
A Clinically Integrated Randomized Clinical Trial (RCT) of Modifications to Radical Cystectomy and Postoperative Care
The purpose of this study is to look at two standard surgical techniques used during a radical cystectomy and see whether they influence outcomes such as length of stay in the hospital and infections after surgery. This trial will evaluate whether the following surgical methods influence outcomes:
A ureteral stent is a thin tube that is placed in the ureter to drain urine from the kidney. Ureteral stents are often used to promote urine drainage after radical cystectomy, but may come at risk of urinary tract infection.
Alvimopan is a standard drug used to promote return of bowel function following surgery. Doctors do not know whether alvimopan is beneficial in current clinical practice.
The surgeon will decide whether participants will receive a stent and/or alvimopan, but if they are unsure what the best approach is, a surgical technique has been assigned by chance to them.
Inclusion: Stent vs. no stent; Patients aged ≥21 years who are scheduled to undergo radical cystectomy for treatment of bladder cancer with one of the consenting surgeons Alvimopan vs. no alvimopan; Patients aged ≥21 years who are scheduled to undergo radical cystectomy for treatment of bladder cancer with one of the consenting surgeons.
Exclusion: Patients on chronic opioid therapy are ineligible to receive alvimopan and will be excluded from this cohort of the trial; Stent vs. no stent; No exclusion criteria; Alvimopan vs. no alvimopan.