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MRI Analysis in the Growth of Cerebral Aneurysms

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  4. What happens if I want to stop?

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Trial details

Who runs it
CHU de Reims
Trial code
NCT06705452
Record updated
7 August 2026
Original description
An intracranial aneurysm is defined as a localized dilatation of the cerebral arteries, which can potentially lead to rupture and subsequent hemorrhagic stroke. The mechanisms by which aneurysms develop and grow remain unknown. The objective of this project is to utilize MRI, a routine non-invasive examination for detecting and following up aneurysms, to identify visually and quantitatively an aneurysm growth and relevant biomarkers that can predict the risk of aneurysm development.Read full original descriptionShow less

4D-MRI Morphological Study of Local Growth in Cerebral Aneurysms

An intracranial aneurysm is defined as a localized dilatation of the cerebral arteries, which can potentially lead to rupture and subsequent hemorrhagic stroke. The mechanisms by which aneurysms develop and grow remain unknown. The objective of this project is to utilize MRI, a routine non-invasive examination for detecting and following up aneurysms, to identify visually and quantitatively an aneurysm growth and relevant biomarkers that can predict the risk of aneurysm development.

Inclusion: Patients with one or more unruptured intracranial aneurysms followed up at the participating center. Patients may have other ruptured and/or treated aneurysms; Patient older than 18 years; Patient consenting to participate to the study; Patient enrolled in the national healthcare insurance program.

Exclusion: Patients who have already received surgical or endovascular treatment for all their aneurysm(s), or who are due to receive such treatment in less than 2 months; Patients with an allergy to one of the contrast agents (Iodixanol, Gadoteric acid); Patients with only ruptured aneurysm(s); Patients with arteriovenous malformations (treated or untreated); Patients with a contraindication to MRI; Pregnant or breast-feeding patients; Patients protected by law.

ClinicalTrials.gov NCT06705452