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Tumor DNA in Drainage Fluid After Prostate Removal Surgery

Studies tumor DNA levels in drain fluid from men after prostate cancer surgery.

Plain-language title generated from the registry record
Registry title: Prognostic Study of Via Dynamic Change of dT-DNA in Drainage Fluid After Radical Prostatectomy

Key facts

Where
Shanghai, ChinaSee the site

Where in China

  • Shanghai General HospitalShanghai, ChinaNo longer taking part

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Trial details

Who runs it
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Trial code
NCT06707974
Record updated
27 November 2024
Original description
This study investigates the prognostic value of dynamic changes in Drainage Tumor DNA(dT-DNA) levels found in the peritoneal drainage fluid after radical prostatectomy. Prostate cancer is one of the most common cancers in men, and radical prostatectomy is a standard treatment. While PSA levels in the blood are commonly used as a marker for diagnosis, this study focuses on the significance of dT-DNA levels in the prognosis of prostate cancer. The findings may provide insights into improved post-surgical monitoring and more tailored therapeutic strategies for prostate cancer patients.Read full original descriptionShow less

Prognostic Study of Prostate Cancer Via Dynamic Change of Drainage Tumor DNA(dT-DNA) in Peritoneal Drainage Fluid After Radical Prostatectomy

This study investigates the prognostic value of dynamic changes in Drainage Tumor DNA(dT-DNA) levels found in the peritoneal drainage fluid after radical prostatectomy. Prostate cancer is one of the most common cancers in men, and radical prostatectomy is a standard treatment. While PSA levels in the blood are commonly used as a marker for diagnosis, this study focuses on the significance of dT-DNA levels in the prognosis of prostate cancer. The findings may provide insights into improved post-surgical monitoring and more tailored therapeutic strategies for prostate cancer patients.

Inclusion: Prostate cancer patients treated with radical prostatectomy.

Exclusion: 1. Received neoadjuvant endocrine/chemotherapy before surgery; 2. Urine leakage after surgery (positive creatinine test of drainage fluid).

ClinicalTrials.gov NCT06707974