Testing a risk model to guide heart tests in people with new chest pain
Tests a chest pain risk model in adults with new stable chest pain.
Plain-language title generated from the registry record
Registry title: Personalized Evaluation of Susptected Myocardial Ischemia
Key facts
- Where
- Herning, DenmarkSee the site
- Phase
- Phase 3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 75 years old?
Source: NCT06708000, who can take part
Where in Denmark
- Regional Hospital of GodstrupHerning, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Gødstrup Hospital
- Trial code
- NCT06708000
- Record updated
- 19 December 2025
- Original description
This study aims to assess whether the use of clinical risk models, known as Clinical Likelihood (CL) models, can reduce the need for diagnostic examinations without negatively impacting quality of life or prognosis after 12 months in patients with stable new onset chest pain. Additionally, the project will evaluate a newly developed method called Laser Speckle Contrast Imaging for measuring function and oxygen content in the smallest blood vessels (microvasculature) of the hand, which may also reflect blood flow and oxygen content in the microvasculature of the heart.Read full original descriptionShow less
Personalized Evaluation of Suspected Myocardial Ischemia
This study aims to assess whether the use of clinical risk models, known as Clinical Likelihood (CL) models, can reduce the need for diagnostic examinations without negatively impacting quality of life or prognosis after 12 months in patients with stable new onset chest pain. Additionally, the project will evaluate a newly developed method called Laser Speckle Contrast Imaging for measuring function and oxygen content in the smallest blood vessels (microvasculature) of the hand, which may also reflect blood flow and oxygen content in the microvasculature of the heart.
Inclusion: Patients with de novo chest pain referred on suspicion of stable ischemic CAD; Patients capable of providing written informed consent.
Exclusion: Known ischemic heart disease, including previous PCI (with or without stent) and bypass surgery; Unstable angina pectoris at initial consultation; Severe valvular disease; Absolute or relative contraindications for Cardiac CT:; allergy to iomeron; LVEF \<45%; Age \<30 years or \>75 years; Severe COPD or asthma; pregnant women, including women who are potentially pregnant or lactating; reduced kidney function with an estimated glomerular filtration rate \<40 ml/min.