Testing a new real-time image guided radiation method in people with cancer
Tests whether real-time image guided radiation therapy is workable for adults with cancer.
Plain-language title generated from the registry record
Registry title: A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods
Key facts
- Where
- Melbourne, AustraliaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who will have radiation therapy meant to remove all of the disease, for one of several cancer types. It tests a real-time image-guided way of giving the radiation.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Cancer of the brain, breast, head and neck, kidney, liver, lung, pancreas, prostate or spine. ECOG performance status 0-2.
- Earlier treatment
- Must be planned for radiation therapy meant to remove all of the disease.
Main reasons for not taking part
- Pregnancy
- Any other serious medical condition that, in the treating doctor's opinion, makes joining undesirable or could affect following the study rules
- Severe psychiatric illness or difficult social situation
- Not able to understand or sign the written consent form
Read by machine on 9 November 2026.
Where in Australia
- Peter MacCallum Cancer CentreMelbourne, AustraliaContact: Nick HardcastleNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Sydney
- Trial code
- NCT06708221
- Record updated
- 20 May 2026
- Original description
The goal of this clinical trial is to determine whether Real-Time Image Guided Radiation Therapy is a feasible method for radiation therapy delivery for patients with cancer.Read full original descriptionShow less
Real-Time IGRT: A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods
The goal of this clinical trial is to determine whether Real-Time Image Guided Radiation Therapy is a feasible method for radiation therapy delivery for patients with cancer.
The main questions it aims to answer are:
* Can all fractions per patient which are intended to be delivered with the real-time IGRT method be completed as planned? * Can the beam accurately hit the tumour in ≥85% of fractions? * Are there any unexpected grade >3 acute toxicities?
Participants will not require any additional treatments or preparation procedures above those required for normal radiation therapy treatment, to participate in this study.
Inclusion: Patients 18 years or older to be treated with curative radiation therapy; Patients with brain, breast, head and neck, kidney, liver, lung, pancreas, prostate or spine cancer; ECOG performance status 0-2; Ability to understand and the willingness to sign a written informed consent document.
Exclusion: Patients with any other clinically significant medical condition which, in the opinion of the treating physician, makes it undesirable for the patient to participate in the study or which could jeopardize compliance with study requirements or severe psychiatric illness/social situation; Pregnancy,; Additional inclusion and exclusion criteria may apply to a specific sub-study.