Tests Salovum and SPC flakes for swelling caused by brain tumors
Tests egg yolk powder and oat flakes in adults with brain tumor swelling.
Plain-language title generated from the registry record
Registry title: Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema
Key facts
- Where
- Lund, SwedenSee the site
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 79 years old?
Source: NCT06710249, who can take part
Where in Sweden
- Department of NeurosurgeryLund, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Peter Siesjö
- Trial code
- NCT06710249
- Record updated
- 27 January 2025
- Original description
The objective of this clinical trial is to explore the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, and SPC® flakes , hydrothermically processed oats, on cerebral edema with clinical symptoms in participants with brain tumors.Read full original descriptionShow less
Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema
The objective of this clinical trial is to explore the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, and SPC® flakes , hydrothermically processed oats, on cerebral edema with clinical symptoms in participants with brain tumors.
The primary questions the trial seeks to answer are:
* Can Salovum® and SPC® flakes have effect on clinical symptoms of tumor-induced cerebral edema? * Can Salovum® and SPC® flakes induce regression of radiological edema in tumor-induced cerebral edema Additionally, the study will investigate the impact of Salovum® and SPC® flakes in steroid refractory, steroid naïve cerebral edema and type of barin tumor
Researchers will:
Evaluate edema change from baseline by MRI after 14 days Evaluate neurological and cognitive symptoms Register dose of steroid medications
Participants will:
* Ingest Salovum® 11g three times daily for 14 days, thereafter tapered during 14 days * Ingest SPC® flakes 1g/kg daily from day 7
Inclusion: Age 18-79 years; Known or radiologically suspected primary or secondary brain tumor (suspected metastasis, meningioma, glioma, etc.) with surrounding edema causing clinical signs; GCS 14-15; WHO ECOG performance status 0-2; Planned or started cortisone treatment; Ability to provide informed consent.
Exclusion: Egg yolk allergy; Epilepsy as sole symptom from the cerebral edema; Midline shift >5mm; GCS ≤13.