Taking people in GermanyNo phase
Compares how long patients stay on upadacitinib versus TNF inhibitors for rheumatoid arthritis
Compares treatment retention of upadacitinib and TNF inhibitors in adults with rheumatoid arthritis.
Plain-language title generated from the registry record
Registry title: A Comparison Study of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German Real-world SettING
Key facts
- Where
- Altenburg, Amberg, Augsburg, Bad Endenbach, Bad Pyrmont, Bamberg, Berlin, Bielefeld, Braunschweig, Chemnitz, Coburg, Daun, Dresden, Düren, Ehringshausen, Elsterwerda, Erfurt, Erlangen, Euskirchen, Frankfurt am Main, Freiberg, Freiburg im Breisgau, Gifhorn, Greifswald, Halle, Hamburg, Hanover, Heidelberg, Herne, Hohen Neuendorf, Homburg, Hoppegarten, Kaiserslautern, Kassel, Kaufering, Leipzig, Ludwigslust, Magdeburg, Marktredwitz, Meerbusch, Monheim am Rhein, Munich, Naumburg, Neubrandenburg, Neunkirchen, Osnabrück, Pfarrkirchen, Planegg, Plauen, Potsdam, Püttlingen, Ratingen, Rendsburg, Schwerin, Templin, Tübingen, Ulm, Waren, Weimar, Weyhe, Wittlich, Wuppertal, Zweibrücken, and Zwickau, GermanySee the 75 sites
Where in Germany
- Private Practice - Dr. Thomas Kupka /ID# 273631Altenburg, GermanyTaking people
- Dr. Med. Thomas Marycz /ID# 274646Amberg, GermanyTaking people
- Rheumapraxis Am Webereck /ID# 274412Augsburg, GermanyTaking people
- Rheumatism Center Mittelhessen /ID# 274641Bad Endenbach, GermanyTaking people
- MVZ Weserbergland /ID# 276009Bad Pyrmont, GermanyNo longer taking part
- Private Practice - Dr. Karin Manger /ID# 287347Bamberg, GermanyTaking people
- Private Practice - Dr. Silke Zinke /ID# 276366Berlin, GermanyTaking people
- Rheumapraxis am Schlachtensee /ID# 287793Berlin, GermanyTaking people
- Rheumapraxis Steglitz /ID# 280323Berlin, GermanyTaking people
- Klinikum Bielefeld Rosenhohe /ID# 283715Bielefeld, GermanyTaking people
- Mvz Dr. Med. Mahdy and Kollegen - Braunschweig /ID# 284988Braunschweig, GermanyTaking people
- MVZ Herzogin Elisabeth Hospital /ID# 272725Braunschweig, GermanyTaking people
- Stadtisches Klinikum Braunschweig /ID# 282626Braunschweig, GermanyTaking people
- Medizinischen Versorgungszentrums Agilomed /ID# 274887Chemnitz, GermanyTaking people
- Private Practice - Dr. Sebastian Schuh /ID# 272731Coburg, GermanyTaking people
- MVZ-Medizinisches Versorgungszentrum Daun GmbH /ID# 285725Daun, GermanyTaking people
- Schwerpunktpraxis Rheumatologie und Klinische Immunologie /ID# 282628Dresden, GermanyTaking people
- Rheumapraxis Düren /ID# 272726Düren, GermanyTaking people
- Praxis Dilltal /ID# 272727Ehringshausen, GermanyTaking people
- Medikomp Mvz /ID# 285898Elsterwerda, GermanyTaking people
- Private Practice - Dr. Daniel Bestler /ID# 272741Erfurt, GermanyTaking people
- Praxisgemeinschaft Rheumatologie Nephrologie Erlangen /ID# 286648Erlangen, GermanyTaking people
- Rheumatology Euskirchen /ID# 285419Euskirchen, GermanyTaking people
- Deutsches Endokrinologisches Versorgungszentrum DEVZ - MVZ GdR /ID# 274291Frankfurt am Main, GermanyTaking people
- Dr. Mueller /ID# 273081Freiberg, GermanyTaking people
- Gemeinschaftspraxis Innere Medizin/Rheumatologie /ID# 278584Freiburg im Breisgau, GermanyTaking people
- Private Practice - Dr. Jorg Sensse /ID# 281907Gifhorn, GermanyTaking people
- Praxis Fiene /ID# 279410Greifswald, GermanyTaking people
- Rheumapraxis Dr. Liebhaber /ID# 274888Halle, GermanyTaking people
- Private Practice - Dr Hauke E Heintz /ID# 278081Hamburg, GermanyTaking people
- Praxis. F. Bigdeli-Wilshusen /ID# 273455Hanover, GermanyTaking people
- Rheumapraxis Hannover-List /ID# 273735Hanover, GermanyTaking people
- Rheumatologische Facharztpraxis /ID# 286591Hanover, GermanyTaking people
- Rheumapraxis Heidelberg /ID# 276475Heidelberg, GermanyTaking people
- Rheumazentrum Ruhrgebiet /ID# 275518Herne, GermanyTaking people
- Private Practice - Dr. Dirk Wernicke /ID# 276820Hohen Neuendorf, GermanyTaking people
- Rheumapraxis am Schlossberg /ID# 272728Homburg, GermanyTaking people
- Praxis K. Pagel /ID# 279121Hoppegarten, GermanyTaking people
- Praxis Dr. med. Florian Beyer /ID# 274293Kaiserslautern, GermanyTaking people
- Rheumatologie Kassel /ID# 275916Kassel, GermanyTaking people
- Rheumapraxis Kaufering /ID# 283852Kaufering, GermanyTaking people
- Private Practice - Dr. Frank Hamann, Dr. Andreas Teich & Dr. Konrad Boche /ID# 275358Leipzig, GermanyTaking people
- Private Practice - Dr. Ilka Schwarze /ID# 276981Leipzig, GermanyTaking people
- Dr. Ann-Dorthe Holst /ID# 285741Ludwigslust, GermanyTaking people
- Private Practice- Dr. Joerdis Gerigk /ID# 283747Magdeburg, GermanyTaking people
- Rheumatologische Facharztpraxis - Magdeburg /ID# 272866Magdeburg, GermanyTaking people
- Dr. Harmuth /ID# 273401Marktredwitz, GermanyTaking people
- St.Elisabeth Hospital Meerbusch /ID# 275030Meerbusch, GermanyTaking people
- Gesundheitscampus Monheim /ID# 283726Monheim am Rhein, GermanyTaking people
- Praxiszentrum Dr. Med. Klaus Kruger Dres. Günther Kellerer Und Paul Kellerer /ID# 276138Munich, GermanyTaking people
- Prof-med-stud.de /ID# 285869Munich, GermanyTaking people
- Rheumatologische Facharztpraxis - Naumburg (Saale) /ID# 272743Naumburg, GermanyTaking people
- Private Practice - Dr. Thilo Klopsch - Stargarder Strasse /ID# 276367Neubrandenburg, GermanyTaking people
- Dr. Murawski /ID# 272724Neunkirchen, GermanyTaking people
- Rheumapraxis An Der Hase /ID# 276949Osnabrück, GermanyTaking people
- Die Fachaerzte im Rottal - Nephrologie, Rheumatologie /ID# 284221Pfarrkirchen, GermanyTaking people
- Klinische Forschung Im Medizinischen Versorgungalltag Gbr /ID# 274587Planegg, GermanyTaking people
- Private Practice - Dr. Christine Baumann /ID# 275095Plauen, GermanyTaking people
- Rheumahaus Studien GbR /ID# 275917Potsdam, GermanyTaking people
- Knappschaftsklinikum Saar /ID# 279852Püttlingen, GermanyTaking people
- Rheumapraxis Dr. Prothmann /ID# 279851Püttlingen, GermanyTaking people
- Rheumazentrum Ratingen /ID# 275707Ratingen, GermanyTaking people
- Private Practice - Dr. Jochen Walter /ID# 280069Rendsburg, GermanyTaking people
- Rheumatologische Facharztpraxis - Schwerin /ID# 284785Schwerin, GermanyTaking people
- Rheumatologisch Immunologisch /ID# 275830Templin, GermanyTaking people
- Rheumapraxis Haas Tubingen /ID# 275536Tübingen, GermanyTaking people
- Rheumapraxis Ulm Dr. med. Nadia Rinaldi /ID# 276293Ulm, GermanyTaking people
- Praxis F. Schattenberg /ID# 280322Waren, GermanyTaking people
- Rheumapraxis Weimar /ID# 272740Weimar, GermanyTaking people
- Fachpraxis fur Rheumatologie und Osteologie /ID# 275359Weyhe, GermanyTaking people
- Private Practice - Dr. Alexander Lautwein /ID# 282328Wittlich, GermanyTaking people
- Cellitinnen-Krankenhaus St. Josef /ID# 275926Wuppertal, GermanyTaking people
- Praxis Barmen /ID# 277514Wuppertal, GermanyTaking people
- Rheumapraxis Zweibruecken - Matar /ID# 282656Zweibrücken, GermanyTaking people
- Praxis H. Fricke-Wagner /ID# 274467Zwickau, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- AbbVie
- Trial code
- NCT06712628
- Record updated
- 15 October 2026
- Original description
This study will compare the retention rates for UPA vs. TNFi treatment in adult participants with moderate to severe active RA per local label and according to local standard of careRead full original descriptionShow less
Comparison of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German Real-world SettING
This study will compare the retention rates for UPA vs. TNFi treatment in adult participants with moderate to severe active RA per local label and according to local standard of care
This is a mono-country, prospective, multi-center observational study in patients with moderate to severe active RA receiving UPA or TNFi therapy. Around 678 participants will be enrolled in approximately 80 sites in Germany.
Study recruitment will last approximately 24 months, and the study participation time will be up to 24 months, for a total study duration of approximately 48 months.
Inclusion: Current or Past participants with a confirmed diagnosis of moderate to severe active RA upon judgement of the treating physician; Physician decision on participant treatment with Upadacitinib (UPA) or tumor necrosis factor inhibitor (TNFi) must have been reached prior to and independently of recruitment in the study; UPA or TNFi prescribed in accordance with the applicable approved label and local regulatory and reimbursement policies.
Exclusion: Participation in a clinical trial with an investigational drug (within a minimum of 30 days or 5 half-lives of the investigational drug [whichever is longer] prior to baseline); Prior treatment with Upadacitinib; Prior treatment with the same tumor necrosis factor inhibitor as the one prescribed for this study.