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Tests electric field stimulation as a possible epilepsy treatment in adults

Tests temporally interfering electric field stimulation in adults with medial temporal lobe epilepsy.

Plain-language title generated from the registry record
Registry title: Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy

Key facts

Where
Brno, CzechiaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with medial temporal lobe epilepsy who are having invasive intracranial EEG studies. It tests a brain stimulation method called temporally interfering electric field stimulation.

Age
18 Years and older
Sex
Women and men can join.
Disease stage
Medial temporal lobe epilepsy.

Read by machine on 12 November 2026.

Where in Czechia

  • St. Anne Hospital, Masaryk UniversityBrno, CzechiaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
University of California, Davis
Trial code
NCT06716866
Record updated
6 August 2026
Original description
This study investigates the potential for temporally-interfering electric field stimulation (TIEFS) to treat epilepsy. In this case series within and between subjects design, the impact of TIEFS on epilepsy biomarkers was studied in patients with medial temporal lobe epilepsy.Read full original descriptionShow less

Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy - Effect of Temporal Interference on Biomarkers of Epilepsy

This study investigates the potential for temporally-interfering electric field stimulation (TIEFS) to treat epilepsy. In this case series within and between subjects design, the impact of TIEFS on epilepsy biomarkers was studied in patients with medial temporal lobe epilepsy.

Secondary analyses examine the underlying physiological effects of TIEF on local brain activity and brain networks.

Inclusion: Patients undergoing invasive intracranial EEG studies.

Exclusion: None.

ClinicalTrials.gov NCT06716866