Scanning Muscle Oxygen Before Head and Neck Reconstructive Surgery
Compares muscle oxygen levels in head and neck cancer patients and healthy adults.
Plain-language title generated from the registry record
Registry title: Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Key facts
- Where
- Erlangen, GermanySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a confirmed head and neck tumor, and also healthy adults. Both groups are scanned with a light-based imaging method to measure tissue oxygen.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Head and neck tumor confirmed by tissue examination (histopathology). No stage is named.
Main reasons for not taking part
- Pregnancy or breastfeeding
- Ink or tattoo in the scan areas (upper back, lower arm, upper and lower leg)
- No signed consent form
- Healthy group: long-term heavy alcohol or nicotine use
Read by machine on 9 November 2026.
Where in Germany
- University Hospital ErlangenErlangen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Erlangen-Nürnberg Medical School
- Trial code
- NCT06716892
- Record updated
- 4 December 2024
- Original description
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue. This proposed study aims to investigate possible limitations of human tissue used for reconstructive surgery due to flawed tissue perfusion.Read full original descriptionShow less
Non-invasive Preoperative Donor-site Evaluation of Free Flaps in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue. This proposed study aims to investigate possible limitations of human tissue used for reconstructive surgery due to flawed tissue perfusion.
Healthy volunteers as well as patients with a diagnosed head and neck cancer entity will be recruited. Both cohorts will then be scanned on different body areas (most common tissue sites used for reconstructive surgery on the back, arms and legs) to assess differences in muscle oxygenation between the healthy and tumor patient cohort using MSOT.
The hypothesis of the study is, that patients with diagnosed head and neck cancer entities are prone to compromised tissue perfusion due to a high prevalence of smoking within the head neck tumor patient cohort and therefore perfusion restirciting diseases e.g. peripheral arterial occlusive disease (PAOD).
Inclusion: Cohort 1: Histopathological diagnosed head and neck tumor patients; Cohort 2: Healthy adults.
Exclusion: Pregnancy / breastfeeding; ink / tattoo in the areas of interest (upper back, distal forearm, upper and lower leg); missing consent form; Cohort 2: Chronical abuse of alcohol and nicotine.