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Blood Test Study Using AI to Detect Cancer Early and Track Treatment

Tests an AI-based blood test in adults with several cancers, including breast and lung.

Plain-language title generated from the registry record
Registry title: The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling

Key facts

Where
Rosario, ArgentinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 40 to 75 with a confirmed diagnosis of one of several common cancers. Blood samples are used to develop an AI-based blood test.

Age
40 to 75 years
Sex
Women and men can join.
Disease stage
Confirmed diagnosis of non-small cell lung cancer, glioblastoma, colorectal cancer, liver cancer (hepatocellular carcinoma), breast cancer, prostate cancer, ovarian cancer or pancreatic cancer. In the second phase: liver cancer or non-small cell lung cancer only.
Earlier treatment
Cannot have used anticoagulant or antiplatelet drugs within the past 2 weeks (first phase).

Main reasons for not taking part

  • Currently pregnant (first phase)
  • Any active infectious disease (first phase)
  • Anticoagulant or antiplatelet drugs within the past 2 weeks (first phase)
  • Another cancer, unless it has been in remission for at least 5 years (second phase)
  • Medical or psychological conditions that make it hard to follow the study steps

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 75 years old?

Source: NCT06717295, who can take part

Where in Argentina

  • Various Cancer CentresRosario, ArgentinaContact: Javier Toledo, Medical DegreeNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Javier Toledo
Trial code
NCT06717295
Record updated
2 January 2026
Original description
The purpose of the CCANED-CIPHER study is to develop and validate an AI-based blood test for early cancer detection and to monitor treatment effectiveness in cancer patients. This two-phase, multi-center observational study aims to identify specific transcriptomic biomarkers in platelets and immune cells that distinguish cancer patients from healthy individuals and correlate with treatment outcomes. By analysing blood samples using artificial intelligence, the study seeks to create a safe, non-invasive method to enhance cancer diagnosis and monitor treatment responses over time.Read full original descriptionShow less

The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling

The purpose of the CCANED-CIPHER study is to develop and validate an AI-based blood test for early cancer detection and to monitor treatment effectiveness in cancer patients. This two-phase, multi-center observational study aims to identify specific transcriptomic biomarkers in platelets and immune cells that distinguish cancer patients from healthy individuals and correlate with treatment outcomes. By analysing blood samples using artificial intelligence, the study seeks to create a safe, non-invasive method to enhance cancer diagnosis and monitor treatment responses over time.

Inclusion: Age: Adults aged 40 years or older; Confirmed diagnosis of one of the following common cancers: Non-Small Cell Lung Cancer (NSCLC), Glioblastoma Multiforme (GBM), Colorectal Cancer, Hepatocellular Carcinoma (HCC), Breast Cancer, Prostate Cancer, Ovarian Cancer, Pancreatic Cancer; Adults aged 40 years or older; Confirmed diagnosis of: Hepatocellular Carcinoma (HCC), Non-Small Cell Lung Cancer (NSCLC); Willingness to provide blood samples at the specified intervals (baseline, 6 weeks, and 6 months post-therapy initiation).

Exclusion: Use of anticoagulant or antiplatelet drugs within the past 2 weeks; Presence of any active infectious diseases; Any medical or psychological conditions that may affect the participant's ability to comply with study procedures; Phase 2 ( Cancer Immuno-Profiling of Hematologic and Extracellular RNA - CIPHER); Presence of another malignancy unless it has been in remission for at least 5 years; Significant uncontrolled co-morbid conditions that may interfere with study participation or outcomes; Currently pregnant.

Phase 1 (Common Cancer Early Detection - CCANED).

ClinicalTrials.gov NCT06717295