Laser Treatment Compared With Open Surgery for Temporal Lobe Epilepsy
Tests laser treatment guided by MRI against open surgery in people with temporal lobe epilepsy.
Plain-language title generated from the registry record
Registry title: MRgLITT for mTLE: A PROBE Trial
Key facts
- Where
- Beijing, ChinaSee the site
Where in China
- Beijing Tiantan HospitalBeijing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Beijing Tiantan Hospital
- Trial code
- NCT06720922
- Record updated
- 21 January 2026
- Original description
How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?Read full original descriptionShow less
Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy: A Prospective, Randomized, Open Blinded, End-point Trial
How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?
Inclusion: 18-65 years; Drug-resistant mesial temporal lobe epilepsy; Seizure frequency ≥ 1 time /month; Participants approved.
Exclusion: History of brain surgery; Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections; Intracranial space occupying lesions.