Tracking Surgical Outcomes for Brain Vessel and Skull Base Conditions
Studies outcomes and their predictors in adults with brain aneurysms, malformations, and skull base tumors.
Plain-language title generated from the registry record
Registry title: Neurosurgical Outcome Network
Key facts
- Where
- Bergamo, Brescia, Catania, Como, Cremona, Florence, Frosinone, Gravedona, Lecco, Legnano, Livorno, Milan, Monza, Palermo, Parma, Pavia, Roma, Rozzano, Sondrio, and Udine, ItalySee the 27 sites
Where in Italy
- 1. ASST Papa Giovanni XXIIIBergamo, ItalyNo longer taking part
- Fondazione Poliambulanza Istituto OspedalieroBrescia, ItalyNo longer taking part
- Spedali Civili BresciaBrescia, ItalyNo longer taking part
- Azienda Ospedaliero Universitaria Policlinico "G. Rodolico - San Marco"Catania, ItalyTaking people
- ASST Lariana, Ospedale S. AnnaComo, ItalyNo longer taking part
- ASST CremonaCremona, ItalyNo longer taking part
- Azienda Ospedaliero-Universitaria CareggiFlorence, ItalyTaking people
- Ospedale F. Spaziani di FrosinoneFrosinone, ItalyTaking people
- Ospedale Moriggia PelasciniGravedona, ItalyNo longer taking part
- Ospedale Alessandro ManzoniLecco, ItalyNo longer taking part
- ASST Ovest MilaneseLegnano, ItalyNo longer taking part
- Ospedali Riuniti di Livorno -Azienda USL Toscana nord ovestLivorno, ItalyTaking people
- Asst Santi Paolo E CarloMilan, ItalyTaking people
- Fondazione IRCCS Istituto Neurologico Carlo BestaMilan, ItalyTaking people
- ASST Fatebenefratelli SaccoMilan, ItalyNo longer taking part
- Fondazione IRCCS Cà Granda Ospedale Maggiore PoliclinicoMilan, ItalyNo longer taking part
- Istituto Clinico Città StudiMilan, ItalyNo longer taking part
- Policlinico di MonzaMonza, ItalyTaking people
- Fondazione IRCCS San Gerardo dei TintoriMonza, ItalyNo longer taking part
- A.R.N.A.S. Ospedali Civico di PalermoPalermo, ItalyTaking people
- Azienda Ospedaliero Universitaria di ParmaParma, ItalyNo longer taking part
- Fondazione IRCCS Policlinico San MatteoPavia, ItalyNo longer taking part
- ASL Roma 1Roma, ItalyTaking people
- Fondazione Policlinico Universitario Gemelli di RomaRoma, ItalyTaking people
- IRCCS Istituto Clinico HumanitasRozzano, ItalyNo longer taking part
- ASST della Valtellina ed Alto LarioSondrio, ItalyNo longer taking part
- Azienda Sanitaria Universitaria Friuli Centrale di UdineUdine, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Trial code
- NCT06724029
- Record updated
- 30 March 2026
- Original description
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a "common language" in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.Read full original descriptionShow less
Neurosurgical Outcome Network Per la Predizione Dell'Outcome in Neurochirurgia
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a "common language" in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.
Inclusion: Neuro-oncological pathology: supratentorial and subtentorial tumors, intra and extra axial tumors excluding the skull base (anterior, middle and posterior fossa; sellar and parasellar region); Basicranial pathology: tumors originating from the anterior cranial fossa, middle cranial fossa and posterior cranial fossa, sellar region with or without supratentorial/parasellar development; Vascular pathology: aneurysms, AVMs, cavernomas, other pathologies (Moyamoya disease, dural fistulas, nontraumatic hematomas); Traumatic pathology: diffuse damage (nonvisible diffuse damage, diffuse damage, diffuse damage with edema, diffuse damage with shift) and focal damage (acute/subacute/chronic subdural hematoma, extradural hematoma, subarachnoid hemorrhage, intraparenchymal hematoma, fractures); hydrocephalus. The inclusion criterion for chronic subdural hematoma is recent bleeding for TBI with CT finding of chronic subdural hematoma candidate for evacuation surgery; Spinal pathology: degenerative cervical (anterior/posterior), myelopathic, and trauma pathology; instrumented, uninstrumented thoracolumbar pathology (disc pathology, canal pathology), and trauma pathology; oncologic spinal pathology; Functional pathology: Parkinson's disease, spasticity, trigeminal neuralgia, craniofacial pain/algia, neuropathic pain, tremor, dystonias, obsessive compulsive disorder, drug-resistant epilepsies, depression. Normotensive hydrocephalus; Peripheral nervous system pathology: peripheral nerve compression syndromes, peripheral nerve and plexus tumors, brachial plexus and peripheral nerve trauma (contusion and section); Malformative pathology: Chiari malformation type 1 and craniostenoses including both those framed in malformative syndromes and those not framed in malformative syndromes (monosutural craniostenoses: trigonocephaly, plagiocephaly, scaphocephaly; multisutural craniostenoses). Malformative hydrocephalus; For cognitive and psychological assessment: age 18 years or older; adequate understanding of Italian language; diagnosis of glioma, meningioma, vascular pathology, spinal pathology.
Exclusion: For cognitive and psychological assessment: patients with psychiatric diseases in history and/or taking psychotropic drugs; presence of overt cognitive decline (not due to the injury) in history; patients younger than 18 years old.