Taking peopleNo phase

Magnetic brain stimulation for nerve pain after spinal cord injury

Tests magnetic stimulation of the brain for nerve pain in people with spinal cord injury.

Key facts

Who runs it: Afyonkarahisar Health Sciences University
Where: Türkiye1 site in 1 countryChoose a country to see its sites
Trial code: NCT06726954
Registry title: Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain
Status: Recruiting
People taking part: 63 people, planned
Started: 16 Dec 2024
Expected to end: 30 Dec 2026
Type of study: Interventional, 3 groupsOne group gets a sham (pretend) treatment, for comparison.
Treatments tested: High-frequency real-time rTMS DLPF cortex protocol
High-frequency real-time rTMS M1 motor cortex protocol
Sham rTMS Protocol
Record updated: 26 June 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a spinal cord injury who have nerve pain (neuropathic pain). It tests magnetic brain stimulation (rTMS) against a sham treatment.

Age: 18 to 75 years
Sex: All sexes
Disease stage: Spinal cord injury diagnosed by a doctor at least 3-months ago. Nerve pain for at least 3-months that has no other cause.
Earlier treatment: People who have ever used antiepileptic (anti-seizure) drugs cannot join.

Main reasons for not taking part

Serious heart disease, uncontrolled high blood pressure, or a pacemaker
Epilepsy, past seizures, or a brain lesion
Metal implants or other reasons TMS cannot be used
Nerve-wasting diseases, memory or thinking problems, or psychiatric disorders other than depression and anxiety
Cancer or current pregnancy

The registry criteria, word for word

Show all 16 criteriaShow less

Who can take part

Aged 18-75 years Physician-diagnosed spinal cord injury for at least 3-months Neuropathic pain for at least 3-months Pain not attributable to any other conditions

Who cannot take part

Metallic implant
Previous seizure
Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, uncontrolled hypertension,arrhythmia, pacemaker)
Neurodegenerative disease
Epilepsy
History of antiepileptic drug use
Infection on the skin in the application area
Having a brain lesion or a history of drug use that will affect the seizure threshold; Any TMS-related contraindications, for example:
Psychiatric disorders (excluding depression and anxiety)
Malignancy
Cognitive dysfunction
Lower extremity peripheral nerve injury
Increased intracranial pressure or uncontrolled migraine
Pacemaker
Current pregnancy

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 18 and 75 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The aim of our study is to investigate the effect of different protocols of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy added to the rehabilitation program on neuropathic pain,depression, quality of life and quality of sleep compared to each other and placebo group in participants with spinal cord injury.

The 3 groups in the trial

First GroupTreatment being tested
High-frequency real-time rTMS protocol It was planned to apply the dorsolateral prefrontal cortex daily at a frequency of 10 Hz for 20 sessions.
Treatment: High-frequency real-time rTMS DLPF cortex protocol
Second GroupTreatment being tested
High-frequency real-time rTMS protocol It was planned to apply the M1 motor cortex daily at a frequency of 10 Hz for 20 sessions.
Treatment: High-frequency real-time rTMS M1 motor cortex protocol
Third GroupSham treatment, for comparison
Sham rTMS Protocol It was planned to apply daily sham rTMS for 20 sessions.
Treatment: Sham rTMS Protocol