Magnetic brain stimulation for nerve pain after spinal cord injury
Tests magnetic stimulation of the brain for nerve pain in people with spinal cord injury.
Key facts
- Who runs it
- Afyonkarahisar Health Sciences University
- Where
- Afyonkarahisar, TürkiyeSee the site
- Trial code
- Registry title
- Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain
- Status
- Recruiting
- People taking part
- 63 people, planned
- Started
- 16 Dec 2024
- Expected to end
- 30 Dec 2026
- Type of study
- Interventional, 3 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- High-frequency real-time rTMS DLPF cortex protocol
- High-frequency real-time rTMS M1 motor cortex protocol
- Sham rTMS Protocol
- Record updated
- 26 June 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a spinal cord injury who have nerve pain (neuropathic pain). It tests magnetic brain stimulation (rTMS) against a sham treatment.
- Age
- 18 to 75 years
- Sex
- All sexes
- Disease stage
- Spinal cord injury diagnosed by a doctor at least 3-months ago. Nerve pain for at least 3-months that has no other cause.
- Earlier treatment
- People who have ever used antiepileptic (anti-seizure) drugs cannot join.
Main reasons for not taking part
- Serious heart disease, uncontrolled high blood pressure, or a pacemaker
- Epilepsy, past seizures, or a brain lesion
- Metal implants or other reasons TMS cannot be used
- Nerve-wasting diseases, memory or thinking problems, or psychiatric disorders other than depression and anxiety
- Cancer or current pregnancy
The registry criteria, word for word
Show all 16 criteriaShow less
Who can take part
- Aged 18-75 years Physician-diagnosed spinal cord injury for at least 3-months Neuropathic pain for at least 3-months Pain not attributable to any other conditions
Who cannot take part
- Metallic implant
- Previous seizure
- Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, uncontrolled hypertension,arrhythmia, pacemaker)
- Neurodegenerative disease
- Epilepsy
- History of antiepileptic drug use
- Infection on the skin in the application area
- Having a brain lesion or a history of drug use that will affect the seizure threshold; Any TMS-related contraindications, for example:
- Psychiatric disorders (excluding depression and anxiety)
- Malignancy
- Cognitive dysfunction
- Lower extremity peripheral nerve injury
- Increased intracranial pressure or uncontrolled migraine
- Pacemaker
- Current pregnancy
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Where in Türkiye
- Afyonkarahisar Health Sciences UniversityAfyonkarahisar, TürkiyeContact: Ayşe Kalender, MDTaking people
About the trial
What the trial wants to find out
The aim of our study is to investigate the effect of different protocols of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy added to the rehabilitation program on neuropathic pain,depression, quality of life and quality of sleep compared to each other and placebo group in participants with spinal cord injury.
The 3 groups in the trial
- First GroupTreatment being tested
High-frequency real-time rTMS protocol It was planned to apply the dorsolateral prefrontal cortex daily at a frequency of 10 Hz for 20 sessions.
Treatment: High-frequency real-time rTMS DLPF cortex protocol
- Second GroupTreatment being tested
High-frequency real-time rTMS protocol It was planned to apply the M1 motor cortex daily at a frequency of 10 Hz for 20 sessions.
Treatment: High-frequency real-time rTMS M1 motor cortex protocol
- Third GroupSham treatment, for comparison
Sham rTMS Protocol It was planned to apply daily sham rTMS for 20 sessions.
Treatment: Sham rTMS Protocol
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Efficacy of Repetitive Transcranial Magnetic Stimulation Therapy in Neuropathic Pain Associated With Spinal Cord Injury; Randomized Controlled Trial
- Plain-language title
- Magnetic brain stimulation for nerve pain after spinal cord injuryGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Fit questions
- Built from NCT06726954, who can take part
- Record updated
- 26 June 2026