Tests a heart-sac opening procedure to prevent irregular heartbeat after heart surgery
Tests whether a posterior pericardiotomy prevents irregular heartbeat in adults after heart surgery.
Plain-language title generated from the registry record
Registry title: Prevention of Atrial Fibrillation After Cardiac Surgery by Pericardiotomy
Key facts
- Where
- Shanghai, ChinaSee the site
Where in China
- Changhai HospitalShanghai, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Changhai Hospital
- Trial code
- NCT06728826
- Record updated
- 14 July 2026
- Original description
PRINCE-CH is a multicentre, randomized controlled trial which evaluates the effectiveness and safety of posterior pericardiotomy in preventing POAF after cardiac surgery in Chinese population.Read full original descriptionShow less
Pericardiotomy for Prevention of Postoperative Atrial Fibrillation After Cardiac Surgery in China
PRINCE-CH is a multicentre, randomized controlled trial which evaluates the effectiveness and safety of posterior pericardiotomy in preventing POAF after cardiac surgery in Chinese population.
Inclusion: Patients older than or equal to 18 years of age; Requiring surgical intervention on proximal aorta, cardiac valves, and/or coronary arteries; Able to provide informed consent.
Exclusion: Disease of the left pleura or previous left thoracotomy; History of atrial fibrillation or flutter; Reoperations/minimally invasive cardiac surgery/emergent presentation; Need for hypothermic circulatory arrest; Chest deformity; Unlikely to participate in follow-up assessments.