Testing a Less Invasive Vein Measure to Predict Fluid Response in Ventilated Adults
Compares a vein pressure measure with existing tests in ventilated adults receiving fluids.
Plain-language title generated from the registry record
Registry title: Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index for Fluid Responsiveness
Key facts
- Where
- Seongnam-si, South KoreaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 19 and 80 years old?
Source: NCT06733389, who can take part
Where in South Korea
- Seoul National University Bundang HospitalSeongnam-si, South KoreaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Seoul National University Bundang Hospital
- Trial code
- NCT06733389
- Record updated
- 17 December 2024
- Original description
Pulse pressure variation (PPV) and pleth variability index (PVI) are widely used in clinical practice as indicators of the responsiveness to fluid therapy in patients receiving mechanical ventilation. PPV, which measures changes in arterial pressure, requires arterial puncture, which is invasive, and PVI, which detects subtle changes in oxygen saturation, requires an expensive, commercial monitoring equipment. In this study, we aimed to measure peripheral venous pressure variation using less invasive waveform variation in peripheral veins and to determine whether this indicator can be clinically used to predict the responsiveness to fluid therapy. In addition, the investigators aimed to confirm the superiority of the indicators by comparing them with the responsiveness to fluid therapy of the PPV and PVI.Read full original descriptionShow less
Comparison of Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index in Predicting Fluid Responsiveness
Pulse pressure variation (PPV) and pleth variability index (PVI) are widely used in clinical practice as indicators of the responsiveness to fluid therapy in patients receiving mechanical ventilation. PPV, which measures changes in arterial pressure, requires arterial puncture, which is invasive, and PVI, which detects subtle changes in oxygen saturation, requires an expensive, commercial monitoring equipment. In this study, we aimed to measure peripheral venous pressure variation using less invasive waveform variation in peripheral veins and to determine whether this indicator can be clinically used to predict the responsiveness to fluid therapy. In addition, the investigators aimed to confirm the superiority of the indicators by comparing them with the responsiveness to fluid therapy of the PPV and PVI.
Inclusion: Patients voluntarily agreed and signed the written informed consent form before participating in the study; Adults aged 19 years or older; American Society of Anesthesiologists physical class (ASA) 1-3; Patients scheduled for elective hepatectomy under general anesthesia; Patients who require arterial pressure monitoring and additional peripheral venous access for routine anesthesia preparation; Non-smokers with normal pulmonary function.
Exclusion: Patients with abnormal findings on electrocardiogram before surgery; Patients who cannot undergo peripheral venous puncture.