NCT06733714Recruiting
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
Source: ClinicalTrials.gov · Last updated 13 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy. Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS) are two promising tools for cognitive remediation in this population. In this exploratory study, we investigate feasibility, tolerability and preliminary effects of the association of both interventions in older adults with cognitive complaints. METHODS Older adults with cognitive complaints are being enrolled for this study, which comprises 5 daily sessions of 30 minutes of DCT using the BrainHQ platform while simultaneously receiving theta tACS (6Hz, 1.6mA) targeting the Left Dorsolateral Prefrontal Cortex.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 5 Dec 2024
- Start date
- 2 Dec 2024
- Primary completion date
- 1 Mar 2027
- Lead sponsor
- Universidade Federal do Rio de Janeiro
- NCT number
- NCT06733714
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 2 Dec 2024 to the primary completion date, 1 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous stroke
Other illness
- Severe psychiatric or neurological disorders
- History of syncope for an unexplained reason or seizure less than a year ago
- Intracranial metallic prosthesis or cardiac pacemaker
Other
- Estimated Intelligence Quotient \<80
- Dependence on psychoactive substances (DSM-V)
- Uncorrected visual/hearing problems
- Use of anticoagulants
- Any contraindication to performing tACS
Who the study is looking for
- Healthy subjects over 50 years old, with cognitive complaints
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clínica da Memória - IPUB / UFRJ Coordinator of this site? Confirm its status | Rio de Janeiro | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.