Combining brain stimulation with computer training to support memory in older adults
Tests brain stimulation with digital cognitive training in older adults who have cognitive complaints.
Plain-language title generated from the registry record
Registry title: Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
Key facts
- Where
- Rio de Janeiro, BrazilSee the site
Where in Brazil
- Clínica da Memória - IPUB / UFRJRio de Janeiro, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universidade Federal do Rio de Janeiro
- Trial code
- NCT06733714
- Record updated
- 13 December 2024
- Original description
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy.Read full original descriptionShow less
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy.
Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS) are two promising tools for cognitive remediation in this population. In this exploratory study, we investigate feasibility, tolerability and preliminary effects of the association of both interventions in older adults with cognitive complaints.
METHODS Older adults with cognitive complaints are being enrolled for this study, which comprises 5 daily sessions of 30 minutes of DCT using the BrainHQ platform while simultaneously receiving theta tACS (6Hz, 1.6mA) targeting the Left Dorsolateral Prefrontal Cortex.
Inclusion: Healthy subjects over 50 years old, with cognitive complaints.
Exclusion: Previous stroke; Severe psychiatric or neurological disorders; History of syncope for an unexplained reason or seizure less than a year ago; Intracranial metallic prosthesis or cardiac pacemaker; Estimated Intelligence Quotient <80; Dependence on psychoactive substances (DSM-V); Uncorrected visual/hearing problems; Use of anticoagulants; Any contraindication to performing tACS.