NCT06734520Recruiting
Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia
Source: ClinicalTrials.gov · Last updated 16 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a single-arm, open label, phase 1 study in subjects with beta-thalassemia. This study will evaluate the safety and efficacy of preconditioning-free super-transplantation on beta-thalassemia pediatric patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3 (estimated)
- First submitted
- 16 Nov 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 1 Jul 2029
- Lead sponsor
- Guangzhou Women and Children's Medical Center
- Diseases
- Thalassaemia
- NCT number
- NCT06734520
What you commit to
- Study type: Interventional
- Planned participants: 3
- From 1 Oct 2024 to the primary completion date, 1 Jul 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants in other drug clinical trials within the past 1 month;
Other
- Mental patients;
- There are no suitable HLA-incompatible donors.
- Other researchers decide that it is not suitable to participate in this researcher.
Who the study is looking for
- Diagnosis of severe β -thalassemia
- Age between 7-10 years old, male and female; Weight \< 40kg
- The patient has or does not have an HLA-compatible or semi-compatible donor, but unconditional transplantation or refusal of blood stem cell transplantation; Patients with thalassemia gene therapy without conditions or refusal;
- There are fully compatible or incompatible HLA donors, and the physical examination meets the donor conditions;
- The patient and family members agree to receive hypertransplant therapy and sign a written informed consent prior to the transplant trial.
Age in the registry: 7 years to 10 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guangzhou Women and Children's Medical Center Affiliated to Guangzhou Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.