Tests high-dose vitamin D for seizures, fatigue, and quality of life in epilepsy
Tests high-dose vitamin D against placebo in people with epilepsy.
Plain-language title generated from the registry record
Registry title: Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study
Key facts
- Where
- Tainan, TaiwanSee the site
Where in Taiwan
- National Cheng Kung University HospitalTainan, TaiwanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chin-Wei Huang
- Trial code
- NCT06736002
- Record updated
- 13 April 2026
- Original description
This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy. Participants will receive vitamin D supplementation, and clinical outcomes will be assessed over time to determine its potential benefits on seizure control and patient-reported outcomes.Read full original descriptionShow less
Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study
This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy. Participants will receive vitamin D supplementation, and clinical outcomes will be assessed over time to determine its potential benefits on seizure control and patient-reported outcomes.
Inclusion: Aged 20 or above (inclusive); Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy); There is no imaging evidence of persistence or expansion of brain damage in the past three years; Subjects or family members (caregivers) can comply with the trial plan and take vitamin D patients.
Exclusion: -.