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Checking Blood Pressure Readings Against Heart Pumping in Critically Ill Patients

Studies whether pulse pressure readings can reflect heart pumping in adults who are critically ill.

Plain-language title generated from the registry record
Registry title: Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study

Key facts

Where
São Paulo, BrazilSee the site

Where in Brazil

  • Hospital Do CoracaoSão Paulo, BrazilTaking people

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Trial details

Who runs it
Pontificia Universidad Catolica de Chile
Trial code
NCT06737614
Record updated
29 May 2025
Original description
The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients.Read full original descriptionShow less

Can Pulse Pressure Assessment at the Bedside Detect Low Values or Track Changes of Stroke Volume in Critically Ill Patients? The Multicenter, Cross-sectional, Observational, ANDROMEDA-PEGASUS Study

The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients.

We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions.

Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.

Inclusion: 18 years; Admitted to ICU; Functioning arterial line in place.

Exclusion: Pregnancy; Inadequate arterial line transduction (see below); Refusal of consent; Patient who requires extracorporeal circulation.

ClinicalTrials.gov NCT06737614