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Modified Surgery Technique Tested for Thyroid Removal Through the Mouth or Under the Chin

Tests a modified muscle-dissection method in people with thyroid nodules or cancer undergoing endoscopic surgery.

Plain-language title generated from the registry record
Registry title: Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy

Key facts

Where
Shanghai, ChinaSee the site

Where in China

  • Shanghai Sixth People's HospitalShanghai, ChinaTaking people

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Trial details

Who runs it
Shanghai 6th People's Hospital
Trial code
NCT06738888
Record updated
8 October 2026
Original description
The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to refine the procedure through a prospective study. As a procedure refinement, a modified strap-muscle dissection technique will be introduced during transoral and submental endoscopic thyroidectomy.Read full original descriptionShow less

A Functional-oriented Modification of TOaST Based on Partial Preservation of the Lines Alba Cervical

The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to refine the procedure through a prospective study. As a procedure refinement, a modified strap-muscle dissection technique will be introduced during transoral and submental endoscopic thyroidectomy.

Inclusion: Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm; Clinical diagnosis of benign thyroid nodule with a maximum diameter not exceeding 6 cm; Absence of suspicious lateral lymph nodes or distant metastases.

Exclusion: Participants with history of neck surgery or radiation; Participants with fusion or fixation of lymph nodes in the neck; Participants with vocal fold fixation by preoperative fibrolaryngoscope; Participants with preoperative examination suggestive of extrathyroidal invasion; Participants with a significantly restricted neck and/or jaw.

ClinicalTrials.gov NCT06738888