Long-term CPAP Effect with Obstructive Sleep Apnea: a Telemedicine-based
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- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT06738940
- Record updated
- 18 December 2024
- Original description
we hypothesize that long-term CPAP could results in increase weight and muscle composite by changing intake content and hormone and the effect was influenced by presence of CVD, social jet lag, and CPAP compliance. The project aims to conduct a telemedicine-based, multicenter, RCTs to compare the effect of 48-week CPAP and usual care on social jet lag, muscular fat, hormone, and attention and memory in 100 participants with moderate-severe OSA.Read full original descriptionShow less
Long-term CPAP Effect on Social Jet Lag, Intake, Muscular Lipid, Hormone, and Cognition in Patients with Obstructive Sleep Apnea: a Telemedicine-based, Multi-center, Randomized Controlled Trial
we hypothesize that long-term CPAP could results in increase weight and muscle composite by changing intake content and hormone and the effect was influenced by presence of CVD, social jet lag, and CPAP compliance. The project aims to conduct a telemedicine-based, multicenter, RCTs to compare the effect of 48-week CPAP and usual care on social jet lag, muscular fat, hormone, and attention and memory in 100 participants with moderate-severe OSA.
Inclusion: age:≧20 year-old; patients with moderate-severe OSA (AHI≥15/hr).
Exclusion: Use anti-inflammatory drugs(in last 2 weeks); has been Spinal Surgery and move difficult; skin allergy; Neurological Disorders(Infection, Stroke, ALS, Myopathy, Brain tumor and Encephalitis); Internal Diseases(cardiovascular disease or coronary artery disease was poorly controlled; chronic heart failure(including NYHA class 3 or more than NYHA class 3); Acromegaly and Parkinson's disease); Psychosis(Schizophrenia, bipolar disorder and depression); Autoimmune disease(System Lupus Erythematosus, Rheumatoid arthritis, Sarcoidosis, Crohn's disease and Ulcerative Colitis); Cancer(in last 5 years); other sleep disorder(Narcolepsy, insomnia and RBD); Chronic Kidney Disease(eGFR<30); wrist tattoos; BMI≧40 kg/m2; COPD(FEV1/FVC<70); Hyperthyroidism or Hypothyroidism; Primary Aldosteronism; Have been diagnosed with obstructive sleep apnea; Illiterate; shift worker; professional driver has severe drowsiness.