Effect of Genicular Nerve Block on Proprioception in Knee Osteoarthritis
Key facts
- Who runs it
- Ankara City Hospital Bilkent
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 40 people enrolled
- Started
- 16 Dec 2024
- Ended
- 8 Apr 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- genicular nerve block
- Exercise
- Record updated
- 9 April 2026
Who can take part
- Age
- 55 years to 75 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 15 criteriaShow less
Who can take part
- Diagnosis of bilateral primary knee osteoarthritis according to ACR (American College of Rheumatology) criteria
- Age between 55 and 75 years
- Presence of knee osteoarthritis classified as Grade 2 or Grade 3 according to the Kellgren-Lawrence grading system on radiographs taken within the last year
- Knee pain lasting longer than 6 months
- Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, total score 48-96
Who cannot take part
- Intra-articular steroid and/or hyaluronate injection into the knee joint within the last 6 months
- Physical therapy targeting the knee within the last 6 months
- History of surgical operation on the knee region
- Presence of an inflammatory disease
- Poor general health condition (e.g., heart failure, advanced asthma, history of malignancy)
- Any endocrine disorder that may cause polyneuropathy
- Severe knee trauma within the last 6 months
- Regular use of NSAIDs within the last 6 months
- Presence of acute synovitis
- Neurological deficits in the lower extremity
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The study was conducted to investigate the effect of genicular nerve block on pain, quality of life, and proprioception, which are already diminished due to the impact of osteoarthritis in individuals with knee osteoarthritis.
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Does genicular nerve block reduce pain and improve the quality of life in patients with knee osteoarthritis? Does genicular nerve block affect proprioception in patients with knee osteoarthritis?
The 2 groups in the trial
- Genicular Nerve Block GroupTreatment being tested
A nerve block will be performed on 22 patients using lidocaine injection under ultrasound guidance. After obtaining informed consent, the procedure will be carried out following sterilization, with 2% lidocaine hydrochloride injected at a total volume of 6 mL, distributed as 2 mL for each of the superomedial, superolateral, and inferomedial branches of the genicular nerve. After the injection, bleeding control will be performed, and the procedure will be concluded. All ultrasound-guided injections will be performed by a single physician, and the examination, investigations, treatment, and clinical evaluations of the patients will be conducted by the physicians participating in the study.
Treatment: genicular nerve block and Exercise
- Exercise groupExisting treatment, for comparison
Exercise group: A home exercise program will be provided, including isometric strengthening exercises for the quadriceps muscles and stretching exercises for the hamstring muscles.
Treatment: Exercise
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Investigation of the Effect of Ultrasound-Guided Genicular Nerve Block on Knee Joint Proprioception in Patients With Chronic Knee Osteoarthritis
- Record updated
- 9 April 2026