Text messages to help women with HIV take their HIV medicine
Tests text messages for women with HIV starting antiretroviral therapy.
Plain-language title generated from the registry record
Registry title: Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters!
Key facts
- Where
- Nairobi, KenyaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adult women with HIV who have had transactional sex in the past 12 months and are not yet on ART. It tests text messages to help them take ART regularly.
- Age
- Older than 18 years (the registry lists a minimum age of 18 years).
- Sex
- Women only.
- Disease stage
- HIV-positive, not yet on ART, with a viral load that can still be detected at the start.
- Earlier treatment
- Must not currently be on ART.
- Biomarker or test result
- HIV-positive. Viral load must be detectable at the start.
Main reasons for not taking part
- Plans to move away in the next 6 months
- Undetectable viral load at the start
- Pregnant
Read by machine on 9 November 2026.
Where in Kenya
- Partner for Health and Development in AfricaNairobi, KenyaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Washington
- Trial code
- NCT06745050
- Record updated
- 12 May 2026
- Original description
The goal of this clinical trial is to learn if an interactive mHealth intervention will be effective in helping HIV-positive women in high-burden settings who are initiating antiretroviral therapy (ART) take their ART regularly as prescribed, effectively reducing their viral load. The main question it aims to answer is:Read full original descriptionShow less
Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters! A Theory-Based mHealth Intervention to Support Early Antiretroviral Adherence in HIV+ African Women Who Engage in Sex Work
The goal of this clinical trial is to learn if an interactive mHealth intervention will be effective in helping HIV-positive women in high-burden settings who are initiating antiretroviral therapy (ART) take their ART regularly as prescribed, effectively reducing their viral load. The main question it aims to answer is:
- Compared to standard of care, will Motivation Matters! (MM!) be significantly more effective at achieving undetectable viral load in women with HIV by month six.
Researchers will compare the undetectable HIV viral load in women who receive individualized text messages (intervention group) in addition to standard care to those who receive standard care alone (control group).
Participants in the intervention group will receive three messages per week in month one, then two messages per week for the six-month intervention period. Participants will be asked to send a brief, standardized reply to each message, indicating that they are doing well or that they have a question or problem. Regardless of study arm, women will receive ART and counseling consistent with Kenyan guidelines.
Inclusion: Age >18; Transactional sex in past 12 months; HIV-positive; Not currently on ART; Enrolled in one of the Sex Workers Outreach Program clinics; Has access to mobile phone; Willing to receive study text messages; Able to read or have someone else read.
Exclusion: Plans to move away in next 6 months; Undetectable viral load at baseline; Pregnant.