Neck Massage Position Tested for Headache Relief in Migraine and Tension Headache
Tests a neck pressure procedure with head lowered in people with migraine or tension headache.
Plain-language title generated from the registry record
Registry title: Carotid Sinus Massage in Trendelenburg Position for Headache Relief
Key facts
- Where
- Trenque Lauquen, ArgentinaSee the site
Where in Argentina
- Hospital Pedro T.Orellana, Trenque LauquenTrenque Lauquen, ArgentinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital Municipal Pedro T. Orellana
- Trial code
- NCT06745648
- Record updated
- 15 June 2025
- Original description
Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types. There is growing evidence suggesting that blood pressure regulation and baroreceptor activity play a role in headache pathophysiology. Carotid sinus massage (CSM), particularly when combined with the modified Trendelenburg position, may modulate autonomic nervous system activity to relieve headache symptoms.Read full original descriptionShow less
Effectiveness of Carotid Sinus Massage in Modified Trendelenburg Position for Acute Headache Episodes: A Pilot Study
Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types. There is growing evidence suggesting that blood pressure regulation and baroreceptor activity play a role in headache pathophysiology. Carotid sinus massage (CSM), particularly when combined with the modified Trendelenburg position, may modulate autonomic nervous system activity to relieve headache symptoms.
An initial open-label pilot study (n = 17) was completed, and the results were published in a preprint server for health sciences, the Medical Research Archive (medRxiv), demonstrating the feasibility, safety, and promising preliminary efficacy of CSM+T. Based on these findings, a follow-up randomized, sham-controlled, parallel-arm trial will further evaluate the efficacy of the treatment.
Inclusion: Participants must be at least 16 years of age; Must have a diagnosis of one of the following, according to the International Classification of Headache Disorders (ICHD-3):; Migraine; Tension-type headache; Mixed headache; The headache episode must have started within the past 24 hours.
Exclusion: Any contraindication to carotid sinus massage, including:; Carotid bruits; Recent myocardial infarction; History of stroke; Known or suspected carotid artery stenosis; Any contraindication to the Trendelenburg position, including:; Increased intracranial pressure; Respiratory distress; Congestive heart failure; History of syncope; History of cardiac arrhythmias.