Studying Lung Bacteria and Immune Responses in Children With Lung Disease
Observes bacteria, immune activity and inflammation in lung fluid from children with lung disease.
Plain-language title generated from the registry record
Registry title: Investigating Novel Strategies in Pediatric Immune Responses and Microbiome Environment: Comprehensive Lung Disease Investigation in Children.
Key facts
- Where
- Aarhus N, DenmarkSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 0 and 17 years old?
Source: NCT06746077, who can take part
Where in Denmark
- Childrens Center for Pulmonary and Allergic diseases, Aarhus University HospitalAarhus N, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Aarhus University Hospital
- Trial code
- NCT06746077
- Record updated
- 29 October 2026
- Original description
The INSPIRE CHILD-study is a clinical research project focused on understanding lung diseases in children. The study aims to explore how the presence of certain bacteria, immune responses, and inflammatory markers in the lungs are connected to different lung diseases in pediatric patients.Read full original descriptionShow less
INSPIRE CHILD: Investigating Novel Strategies in Pediatric Immune Responses and Microbiome Environment: Comprehensive Lung Disease Investigation in Children
The INSPIRE CHILD-study is a clinical research project focused on understanding lung diseases in children. The study aims to explore how the presence of certain bacteria, immune responses, and inflammatory markers in the lungs are connected to different lung diseases in pediatric patients.
Background:
Lung diseases in children can have long-lasting effects on their health, not only during childhood but also as they grow into adults. However, the specific causes and mechanisms behind these diseases are not yet fully understood. The INSPIRE CHILD-study is designed to investigate whether children with various lung conditions have distinct differences in the types of bacteria, immune system activity, and inflammation in their lungs.
Hypothesis:
Different lung diseases in children are hypothesized to be associated with unique patterns of bacteria, immune responses, and inflammation in the lungs By studying these patterns, the investigators hope to gain new insights that could lead to better diagnostic tools and more personalized treatments for children suffering from lung diseases.
Children already scheduled to undergo bronchoscopy are included in the study. A small sample of fluid from the lungs is collected, and the sample is analyzed for bacteria, immune markers, and signs of inflammation. This research could pave the way for improved care and treatment for young patients with lung conditions.
Inclusion: Age ranging from new-born to 17 years of age; Diagnosed with or being assessed for a lung disease; Possible to sample at least 2 ml of BAL-fluid besides the scheduled amount during the bronchoscopy.
Exclusion: Not undergoing diagnosis at Childrens Center for Pulmonary and Allergic diseases; Failure to meet the requirement of being able to sample an additional 2 ml of BAL-fluid; Age older than 17 years.