Imaging Carotid Artery Plaque to Study Links With Stroke
Studies whether bleeding inside carotid artery plaque on MRI links to later stroke events.
Plain-language title generated from the registry record
Registry title: Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage
Key facts
- Where
- Munich, GermanySee the site
Where in Germany
- Institute for Stroke and Dementia ResearchMunich, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Ludwig-Maximilians - University of Munich
- Trial code
- NCT06749106
- Record updated
- 24 January 2025
- Original description
The aim of this study is to investigate the association between intraplaque hemorrhage (IPH) detected by non-contrast magnetic resonance imaging (MRI) of the carotid artery in routine clinical practice and ipsilateral acute ischemic events. The investigators' overarching aim is to determine whether this sequence aids the diagnostic work-up of stroke patients.Read full original descriptionShow less
Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage
The aim of this study is to investigate the association between intraplaque hemorrhage (IPH) detected by non-contrast magnetic resonance imaging (MRI) of the carotid artery in routine clinical practice and ipsilateral acute ischemic events. The investigators' overarching aim is to determine whether this sequence aids the diagnostic work-up of stroke patients.
For this purpose, the investigators set up a prospective single-center longitudinal observational study with one year follow-up. In addition, this study will analyze retrospectively obtained data collected through clinical routine.
Inclusion: Patients with acute ischemic stroke; Availability of non-contrast carotid MRI scans obtained through routine diagnostic work-up.
Exclusion: Prior stenting of a carotid artery or carotid endarterectomy; Age < 18 years; Infarct in the posterior circulation or bilateral ischemic infarcts; Time between symptom onset and non-contrast carotid MRI > 10 days; Life expectancy < 1 year; Inability to provide written informed consent; This eligibility criteria apply for the prospective part of the PARADE study.