Testing mailed self-sampling kits for cervical cancer screening in women
Tests mailed HPV self-sampling kits for cervical cancer screening in women aged 30 to 65.
Key facts
- Who runs it
- International Agency for Research on Cancer
- Where
- Reims and Troyes, FranceSee the 2 sites
- Trial code
- Registry title
- HPV Self-sampling in the General Population
- Status
- Recruiting
- People taking part
- 6,000 people, planned
- Started
- 26 Jun 2025
- Expected to end
- 31 Dec 2026
- Type of study
- Interventional, 3 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Women receive invitation letter with HPV self-sampling kit
- Women receive invitation letter with choice of ordering a free self-sampling kit or visit healthcare provider
- Record updated
- 23 July 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 30 to 65 living in the Marne and Aube areas of France who are getting their first invitation to cervical cancer screening.
- Age
- 30 to 65 years
- Sex
- Women only
- Disease stage
- Women at moderate risk of cervical cancer who are invited to the organised screening programme for the first time in this round (not a reminder letter).
- Earlier treatment
- Women with a total hysterectomy cannot join.
Main reasons for not taking part
- Under 30 years old, or 66 years old and more
- Already taking part in the current screening round
- Total hysterectomy
- History of cervical cancer
- Current follow-up for an abnormal screening result or cervical lesions
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Women aged 30 to 65 years old
- Living in the study area (Departments of Marne and Aube, France)
- At moderate risk of cervical cancer, i.e. eligible to the organised programme and receiving the first invitation of the screening round (not a reminder letter)
Who cannot take part
- History of cervical cancer
- Outside the target age (less than 30 years old, or 66 years old and more)
- Already participating in the current screening round
- Total hysterectomy
- Current follow-up for abnormal cervical screening result or cervical lesions
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 65 years old?
Where in France
- Regional Cancer Screening Coordinating Centre, Marne siteReims, FranceContact: Aurélie BERTRAND-BRICE, MDTaking people
- Regional Cancer Screening Coordinating Centre, Aube siteTroyes, FranceContact: Lucie FIEVET, MDTaking people
About the trial
What the trial wants to find out
A randomized controlled trial comparing three strategies for cervical cancer screening: direct mailing of HPV self-sampling kit ("Outreach" arm), choice between self-sampling or healthcare provider sampling ("Choice" arm), and standard care (control arm) in two French departments.
The 3 groups in the trial
- OutreachTreatment being tested
Women receive invitation letter with HPV self-sampling kit; Direct mailing of HPV self-sampling kit; Women receive HPV self-sampling kit with instructions; SMS reminder at 3 months if no participation; Assistance provided for triage cytology if HPV positive.
Treatment: Women receive invitation letter with HPV self-sampling kit
- ChoiceTreatment being tested
Women receive an invitation letter offering a choice between ordering a free self-sampling kit or visiting a healthcare provider. Option between self-sampling and healthcare provider: women can choose testing method. If self-sampling chosen, kit sent to home. SMS reminder at 3 months if no participation.
Treatment: Women receive invitation letter with choice of ordering a free self-sampling kit or visit healthcare provider
- Control armNo study treatment, for comparison
Standard invitation to visit healthcare provider for cervical cancer screening. Standard screening procedure. Follow standard organized screening program procedure. HPV self-sampling offered at 12-month reminder if no participation.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- HPV Self-sampling in the General Population: Efficacy, Feasibility, Acceptability and Cost-effectiveness
- Plain-language title
- Testing mailed self-sampling kits for cervical cancer screening in womenGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06749847, who can take part
- Record updated
- 23 July 2025