Studies tiny blood vessels in the eye in people with Fabry disease
Observes retinal blood vessels in adults with Fabry disease, looking for a noninvasive marker.
Plain-language title generated from the registry record
Registry title: Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study
Key facts
- Where
- München, GermanySee the site
Where in Germany
- Department of nephrology, Klinikum rechts der IsarMünchen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Technical University of Munich
- Trial code
- NCT06758648
- Record updated
- 6 January 2025
- Original description
This study aims to gain a deeper understanding of endothelial dysfunction in patients with Fabry disease through a prospective study of the retinal microvasculature and to identify an objective, non-invasive marker to assess disease severity and cardiovascular risk in patients.Read full original descriptionShow less
Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study
This study aims to gain a deeper understanding of endothelial dysfunction in patients with Fabry disease through a prospective study of the retinal microvasculature and to identify an objective, non-invasive marker to assess disease severity and cardiovascular risk in patients.
The main questions addressed are: Do dynamic and static retinal vessel analysis parameters differ from those in healthy individuals? Can these parameters predict cardiovascular and/or Fabry-related events during follow-up? Do these parameters change during follow-up in patients with a non-stable disease?
Inclusion: Age > 18 years; Diagnosis of Fabry disease by genetic testing or GB3 activity in leukocytes; Signed informed consent form.
Exclusion: Surgery less than 2 weeks prior to inclusion in the study; Active infection or cancer; Known epilepsy; Known glaucoma; Lack of capacity to give consent; lack of informed consent.