Tests a Mediterranean-style diet with fermented foods in rheumatoid arthritis
Tests a Mediterranean-style diet with fermented foods in adults with rheumatoid arthritis.
Plain-language title generated from the registry record
Registry title: The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
Key facts
- Where
- Lisbon, PortugalSee the 2 sites
Where in Portugal
- Faculdade Medicina de LisboaLisbon, PortugalTaking people
- Unidade Local de Saúde de Santa MariaLisbon, PortugalTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
- Trial code
- NCT06758817
- Record updated
- 6 January 2025
- Original description
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.Read full original descriptionShow less
The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
Inclusion: RA patients (ACR/EULAR2010 criteria); Age >18-years; Disease duration >1-year; Active disease (DAS28 > 2.6units); On stable medication for 12 weeks; Low/medium MedDiet adherence (PREDIMED<10); Willing to comply with study protocol.
Exclusion: Antibiotic therapy 4-weeks prior to baseline; Inflammatory or irritable bowel disease; Celiac disease; Diabetes; Other immune-mediated inflammatory diseases besides RA; Cancer diagnosed in the last five years; Health conditions which may difficult participation (cognitive impairment/psychiatric disease); Prednisolone dose ≥ 7.5 mg/day; Persistent use of NSAID's; Chronic diarrhea; Major organ dysfunction; Pregnant or lactating individuals.