Tests the ELIOS laser during combined cataract and glaucoma eye surgery
Tests a laser device in adults with glaucoma having combined cataract and glaucoma surgery.
Plain-language title generated from the registry record
Registry title: Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery
Key facts
- Where
- Avranches, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06760169, who can take part
Where in France
- Hôpital Privé de la BaieAvranches, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hôpital Privé de la Baie
- Trial code
- NCT06760169
- Record updated
- 30 September 2026
- Original description
Glaucoma is an irreversible optic neuropathy. It is the second most common cause of blindness worldwide. Glaucoma can be treated with topical medications (eye drops), laser or surgery. Traditional surgery is invasive and has a high complication rate (hypotonia, endophthalmitis, cataracts, etc.). As a result, several types of micro-invasive surgery (MIGS) have been developed to reduce the risks of surgery while maintaining their effectiveness in lowering intraocular pressure (IOP). The ELIOS laser system is the only ophthalmological excimer laser designed for the surgical treatment of glaucoma. The aim of the procedure is to ablate the trabecular meshwork and inner wall of Schlemm´s canal ab interno, with the creation of 10 microchannels of 210 um in the trabeculum using the ELIOS laser with a wavelength of 308 nm, in order to improve trabecular outflow to achieve a reduction in IOP. The ELIOS laser is an example of Microinvasive Glaucoma surgery (MIGS) with published results demonstrating efficacy and safety. The ELIOS laser is already in use in France (AMM / CE mark achieved). Its use as part of a prospective interventional study will enable us to collect data in order to treat patients more effectively and improve the quality of care provided to glaucoma patients.Read full original descriptionShow less
Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery
Glaucoma is an irreversible optic neuropathy. It is the second most common cause of blindness worldwide. Glaucoma can be treated with topical medications (eye drops), laser or surgery. Traditional surgery is invasive and has a high complication rate (hypotonia, endophthalmitis, cataracts, etc.). As a result, several types of micro-invasive surgery (MIGS) have been developed to reduce the risks of surgery while maintaining their effectiveness in lowering intraocular pressure (IOP). The ELIOS laser system is the only ophthalmological excimer laser designed for the surgical treatment of glaucoma. The aim of the procedure is to ablate the trabecular meshwork and inner wall of Schlemm´s canal ab interno, with the creation of 10 microchannels of 210 um in the trabeculum using the ELIOS laser with a wavelength of 308 nm, in order to improve trabecular outflow to achieve a reduction in IOP. The ELIOS laser is an example of Microinvasive Glaucoma surgery (MIGS) with published results demonstrating efficacy and safety. The ELIOS laser is already in use in France (AMM / CE mark achieved). Its use as part of a prospective interventional study will enable us to collect data in order to treat patients more effectively and improve the quality of care provided to glaucoma patients.
Inclusion: Patients ≥ 18 years of age who agree to take part in the study and have signed an informed consent form; Visually significant cataract with indication for surgery; Primary open-angle glaucoma, or secondary open-angle glaucoma (pseudoexfoliative glaucoma or pigmentary glaucoma) with indication for cataract surgery; Open iridocorneal angle (Shaffer classification grade 2-4); Early to moderate glaucoma (advanced glaucoma, with MD from VFs worse than -12dB, will be excluded).
Exclusion: History of intraocular surgery, trauma, or conjunctival scarring in the quadrant intended for surgery; Autoimmune disorder, especially collagenosis; <18 years of age; Presence of severe systemic pathologies 2024-A01891-46_Protocol_V6_21112024_Elios Page 20 / 58; Pregnant or breastfeeding women; Presence of other ophthalmological pathologies (except cataracts), and exclusion of severe dry eye; Visual acuity worse than "counting fingers"; Closure of the iridocorneal angle (and angle-closure glaucoma), angle-closure glaucoma secondary to iridocorneal synechiae, neovascular glaucoma or neovascularization of the iris; Normal-pressure glaucoma; Pachymetry < 490 um or > 620 μm; Glaucomatous visual field with mean deviation worse than ≤-12 dB; IOP > 35 mmHg; Patient under protective supervision; Patient not covered by a social security scheme.