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Long-term Impact of Inhaled Tobramycin for Pseudomonas Aeruginosa Eradication in Bronchiectasis (ERASE II)

Key facts

Where
Anning, Beijing, Changchun, Changsha, Chengdu, Chongqing, Dalian, Fuzhou, Guangzhou, Guiyang, Haikou, Hangzhou, Hefei, Huzhou, Jiaxing, Jinan, Kunming, Nanchang, Nanjing, Nanning, Nantong, Ningbo, Qingdao, Shanghai, Shangrao, Shenyang, Shenzhen, Suzhou, Taiyuan, Wenzhou, Wuhan, Yangzhou, Zhanjiang, and Zhengzhou, ChinaSee the 58 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT06760273, who can take part

Where in China

  • The First People's Hospital of Anning City Affiliated to Kunming University of Science and TechnologyAnning, ChinaContact: Jian He, MDTaking people
  • Beijing Chao-Yang Hospital, Capital Medical UniversityBeijing, ChinaContact: Zhao-hui Tong, MDTaking people
  • Peking Union Medical College Hospital, Chinese Academy of Medical SciencesBeijing, ChinaContact: Xin-lun Tian, MDTaking people
  • The first Affiliated Hospital of Jilin UniversityChangchun, ChinaContact: Dan Li, MDTaking people
  • The Second Xiangya Hospital of Central South UniversityChangsha, ChinaContact: Hong Luo, MDTaking people
  • Xiangya Hospital Central South UniversityChangsha, ChinaContact: Yuan-yuan Li, MDTaking people
  • West China Hospital of Sichuan UniversityChengdu, ChinaContact: Hong Fan, MDTaking people
  • The Third Affiliated Hospital of Chongqing Medical UniversityChongqing, ChinaContact: Chang-zheng Wang, MDTaking people
  • The Second Affiliated Hospital of Chongqing Medical UniversityChongqing, ChinaContact: Jin-Fu XuNo longer taking part
  • The Second Affiliated Hospital of Dalian Medical UniversityDalian, ChinaContact: Qi Wang, MDTaking people
  • Fujian Provincial HospitalFuzhou, ChinaContact: Bao-song Xie, MDTaking people
  • The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, ChinaContact: Wei-jie Guan, PhDTaking people
  • The First Affiliated Hospital of Guangzhou University of Traditional Chinese MedicineGuangzhou, ChinaContact: Shao-feng Zhan, MDTaking people
  • Guizhou Provincial People's HospitalGuiyang, ChinaContact: Lin Liu, MDTaking people
  • Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)Haikou, ChinaContact: Jin-Fu XuNo longer taking part
  • The Affiliated Hospital of Hangzhou Normal UniversityHangzhou, ChinaContact: Qun Lv, MDTaking people
  • The Second Affiliated Hospital of Zhengjiang UniversityHangzhou, ChinaContact: Wen Li, MDTaking people
  • Anhui Chest HospitalHefei, ChinaContact: Hua Niu, MDTaking people
  • The First Affiliated Hospital of Anhui Medical UniversityHefei, ChinaContact: Xiao-yun Fan, MDTaking people
  • Huzhou Central HospitalHuzhou, ChinaContact: Bin Wang, MDTaking people
  • The First Hospital of Jiaxing CityJiaxing, ChinaContact: Xiao-dong Lv, MDTaking people
  • The Second Hospital of Jiaxing CityJiaxing, ChinaContact: Jin-Fu XuNo longer taking part
  • Qilu Hospital of Shandong UniversityJinan, ChinaContact: De-dong Ma, MDTaking people
  • The First Affiliated Hospital of Shandong First Medical UniversityJinan, ChinaContact: Jin-Fu XuNo longer taking part
  • The First Affiliated Hospital of Kunming Medical UniversityKunming, ChinaContact: Jin-Fu XuNo longer taking part
  • The First Affiliated Hospital of NanChang UniversityNanchang, ChinaContact: Wei Zhang, MDTaking people
  • The Second Affiliated Hospital of Nanjing Medical UniversityNanjing, ChinaContact: Gan-zhu Feng, MDTaking people
  • The First Affiliated Hospital of Guangxi Medical UniversityNanning, ChinaContact: Jin-Fu XuNo longer taking part
  • Affiliated Hospital Nantong UniversityNantong, ChinaContact: Jian Feng, MDTaking people
  • The Sixth People's Hospital of Nantong CityNantong, ChinaContact: Hong-yan Gu, MDTaking people
  • Fenghua District People's Hospital of Ningbo CityNingbo, ChinaContact: Zhi Yuan, MDTaking people
  • Ningbo Medical Center Lihuili HospitalNingbo, ChinaContact: Jing-bo Jiang, MDTaking people
  • The First Affiliated Hospital of Ningbo UniversityNingbo, ChinaContact: Chao Cao, MDTaking people
  • QingDao Municipal HospitalQingdao, ChinaContact: Xue-dong Liu, MDTaking people
  • Baoshan District Hospital of Integrated Traditional Chinese and Western MedicineShanghai, ChinaContact: Li Li, MDTaking people
  • Ruijin hospitalShanghai, ChinaContact: Jie-ming Qu, MDTaking people
  • Shanghai Eighth People's HospitalShanghai, ChinaContact: De-jie Chu, MDTaking people
  • Shanghai General HospitalShanghai, ChinaContact: Min Zhang, MDTaking people
  • Shanghai Pulmonary HospitalShanghai, ChinaContact: Jin-Fu Xu, PhDTaking people
  • Shanghai Putuo District People's HospitalShanghai, ChinaContact: Feng-ying Zhang, MDTaking people
  • Shanghai Sixth People's HospitalShanghai, ChinaContact: Tao Ren, MDTaking people
  • The Shanghai Fifth People's HospitalShanghai, ChinaContact: Zhi-Jun Jie, MDTaking people
  • Zhongshan Hospital,Fudan UniversityShanghai, ChinaContact: Yuan-lin Song, MDTaking people
  • Shangrao People's HospitalShangrao, ChinaContact: Qing-wei Meng, MDTaking people
  • Shengjing Hospital Of China Medical UniversityShenyang, ChinaContact: Yu Chen, MDTaking people
  • The First Affiliated Hospital of China Medical UniversityShenyang, ChinaContact: Wei Wang, MDTaking people
  • Shenzhen Institute of Respiratory DiseasesShenzhen, ChinaContact: Ling-wei Wang, MDTaking people
  • The Eighth Affiliated Hospital of Sun Yat-sen UniversityShenzhen, ChinaContact: Jian-quan Zhang, MDTaking people
  • Suzhou Science and Technology Town HospitalSuzhou, ChinaContact: Chao Yang, MDTaking people
  • The First Affiliated Hospital of Soochow UniversitySuzhou, ChinaContact: Jian-an Huang, MDTaking people
  • Shanxi Bethune HospitalTaiyuan, ChinaContact: Jin-Fu XuNo longer taking part
  • The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, ChinaContact: Yu-ping Li, MDTaking people
  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, ChinaContact: Min Xie, MDTaking people
  • Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, ChinaContact: Yang Jin, MDTaking people
  • Subei People's HospitalYangzhou, ChinaContact: Xing-xiang Xu, MDTaking people
  • Affiliated Hospital, Guangdong Medical CollegeZhanjiang, ChinaContact: Jin-Fu XuNo longer taking part
  • Henan Provincial People's HospitalZhengzhou, ChinaContact: Xiao-ju Zhang, MDTaking people
  • Zhengzhou People's HospitalZhengzhou, ChinaContact: Jin-guang Jia, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Shanghai Pulmonary Hospital, Shanghai, China
Trial code
NCT06760273
Record updated
1 April 2025
Original description
The ERASE II study is a prospective follow-up study designed to assess the long-term impact of successful eradication of Pseudomonas aeruginosa (PA) in patients with bronchiectasis. Building on the findings of the initial ERASE study, which evaluated the efficacy and safety of Tobramycin Inhalation Solution, ERASE II aims to determine whether successful PA eradication influences patient prognosis over an extended period.Read full original descriptionShow less

Extended Observational Study on the Long-term Impact of Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Patients With Bronchiectasis: The ERASE II Study

The ERASE II study is a prospective follow-up study designed to assess the long-term impact of successful eradication of Pseudomonas aeruginosa (PA) in patients with bronchiectasis. Building on the findings of the initial ERASE study, which evaluated the efficacy and safety of Tobramycin Inhalation Solution, ERASE II aims to determine whether successful PA eradication influences patient prognosis over an extended period.

The study will involve a total observation period of 36 months, consisting of the initial 9 months of the ERASE study followed by an additional 27 months of comprehensive follow-up. Key outcomes to be assessed include patients' quality of life, lung function, frequency of pulmonary exacerbations, frequency of hospitalization, and overall treatment costs. Additionally, the study will examine the timing and incidence of any potential reinfections with Pseudomonas aeruginosa.

Inclusion: all patients who participate the ERSE study; write the informed consent form.

Exclusion: patients who were lost of follow up in the ERASE study; ineligible for inclusion at the discretion of the researcher for other reasons.

ClinicalTrials.gov NCT06760273