Taking people in SwitzerlandNo phase

Mesh support to prevent hernias after open aortic aneurysm surgery

Looks at mesh added during closure to prevent hernias after aortic aneurysm repair.

Key facts

Who runs it: Hôpital Fribourgeois
Where: Villars-sur-Glâne, SwitzerlandSee the site
Trial code: NCT06762561
Registry title: Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair
Status: Recruiting
People taking part: 20 people, planned
Started: 1 Jun 2025
Planned end: 31 Oct 2026
Type of study: Observational
Treatments tested: Prophylactic retromuscular mesh reinforcement
Record updated: 3 June 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had open surgery to repair an abdominal aortic aneurysm (a bulge in the main belly artery), with a preventive mesh placed in the belly wall, between January 2019 and January 2024. It looks back at their records to see if the mesh prevents hernias at the scar.

Age: 18 years and older
Sex: All sexes
Disease stage: People who already had open abdominal aortic aneurysm repair.
Earlier treatment: Must have had open abdominal aortic aneurysm repair with preventive retromuscular mesh (mesh placed behind the belly muscles) between January 2019 and January 2024.

Main reasons for not taking part

Incomplete or missing medical records from before, during or after surgery
A later belly operation that cut or stitched the mesh, followed by a hernia at the scar
Did not attend the clinical follow-up visit at least one year after surgery
No signed general consent for the use of medical data in research

The registry criteria, word for word

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Who can take part

Adult patients (≥18 years old) who underwent open abdominal aortic aneurysm (AAA) repair with prophylactic retromuscular mesh reinforcement between January 2019 and January 2024
Availability of complete medical records, including preoperative history, surgical details, and postoperative follow-up data
Attendance at a clinical follow-up examination at least one year after the procedure
General informed consent signed for the use of medical data for research purposes

Who cannot take part

Patients with incomplete or missing medical records, including preoperative, intraoperative, or follow-up data
Patients who required a re-laparotomy involving incision or suture of the prophylactic mesh and subsequently developed an incisional hernia
Patients who did not attend the required clinical follow-up examination at least one year postoperatively

Where in Switzerland

HFR Hopitaux FribourgeoisVillars-sur-Glâne, SwitzerlandContact: Melissa Lagger, med. diplTaking people

About the trial

What the trial wants to find out

The goal of this retrospective observational study is to evaluate whether prophylactic mesh reinforcement during abdominal wall closure can prevent incisional hernias (IH) in patients undergoing open abdominal aortic aneurysm (AAA) repair. The main questions it aims to answer are:

Read full original descriptionShow less

* Does mesh reinforcement reduce the incidence of incisional hernias? * What is the frequency of associated postoperative complications? Researchers will compare the outcomes of patients who underwent mesh-reinforced closures to literature-reported outcomes for non-mesh cases to assess differences in IH incidence and complications.

Participants will:

* Undergo clinical follow-ups and abdominal ultrasounds to detect IH. * Complete quality-of-life questionnaires (EQ-5D and PROMIS).

The group in the trial

Prophylactic mesh reinforcement after open aortic aneurysm repair
Patients who underwent open abdominal aortic aneurysm (AAA) repair with prophylactic retromuscular mesh reinforcement at the Fribourg Cantonal Hospital between 2019 and 2024.
Treatment: Prophylactic retromuscular mesh reinforcement