Tests brain stimulation for hand weakness after stroke
Tests repeated magnetic brain stimulation in adults with chronic stroke and arm weakness.
Plain-language title generated from the registry record
Registry title: The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
Key facts
- Where
- Durham, United StatesSee the site
Where in United States
- Duke University Medical CenterDurham, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Duke University
- Trial code
- NCT06765642
- Record updated
- 22 May 2026
- Original description
The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.Read full original descriptionShow less
Evaluation of 3 Patterned rTMS Stimulation Dosage on Corticospinal Excitability and Motor Learning in Stroke Patients
The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.
Inclusion: Age >=21 years old of any race or gender; First-ever ischemic or hemorrhagic stroke (neuroimaging verified) at least 3 months from stroke onset; Unilateral arm weakness measured by FM-UM scale <= 62 out of 66; Inducible rest motor threshold and testing motor threshold recorded from the affected first dorsal interosseous (FDI) muscle from the study subject.
Exclusion: Presence of any MRI/rTMS risk factors including but not limited to:; an electrically, magnetically, or mechanically activated metallic or nonmetallic implant including cardiac pacemaker, intracerebral vascular clips or any other electrically sensitive support system; a non-fixed metallic part in any part of the body, including a previous metallic injury to the eye; history of seizure disorder before stroke or seizure after stroke; preexisting scalp lesion or bone defect or hemicraniectomy; Concurrent enrollment in another interventional stroke recovery study; Other co-existent neuromuscular disorders affecting upper extremity motor impairment; History of medically uncontrolled depression or other neuropsychiatric disorders despite medications either before or after a stroke that may affect the subject's ability to participate in the study; Uncontrolled hypertension despite medical treatment(s) at the time of randomization, defined as SBP≥185 mmHg or DBP≥110 mmHg (patient can be treated, reassessed and randomized later); Bilateral strokes (infarcts and/or hematoma); Concerns that the subject cannot comply with study procedures and visits; Pregnant individuals.