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Brain stimulation with walking and pedaling exercises for stroke patients

Tests brain stimulation with thinking-and-moving exercises in adults over 50 after stroke.

Key facts

Who runs it
The Hong Kong Polytechnic University
Where
Hong Kong, Hong KongSee the site
Trial code
Registry title
Dual-task Training Combined With tDCS on Cognitive-motor Performance and Brain Activity in Stroke Patients
Status
Recruiting
People taking part
72 people, planned
Started
1 Jan 2025
Expected to end
30 Apr 2027
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • active tDCS with dual-task training
  • sham tDCS with dual-task training
Record updated
14 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 50 or more who had a single-sided stroke more than 6 months ago, can walk 10 meters, and live in the community.

Age
50 years or older
Sex
All sexes can join.
Disease stage
Stroke on one side of the brain, with onset more than 6 months ago; able to walk 10 meters with or without a mobility aid; living in the community.
Earlier treatment
People receiving any formal rehabilitation training cannot join.
Biomarker or test result
Montreal Cognitive Assessment score of 22 or higher.

Main reasons for not taking part

  • Other neurological disorders, or pain or another illness that prevents walking
  • Receiving any formal rehabilitation training
  • Reasons not to exercise, such as unstable angina
  • Reasons not to have fNIRS, MRI or tDCS, such as a pacemaker or metal implants in the brain
  • History of seizure or epilepsy, or color blindness

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • a diagnosis of stroke, stroke onset of more than 6 months,
  • aged 50 or more,
  • capable of following verbal and visual instructions,
  • having a Montreal Cognitive Assessment score ≥ 22,
  • able to walk for 10 meters with/without a mobility aid,
  • community-dwelling, unilateral stroke

Who cannot take part

  • receiving any formal rehabilitation training,
  • contraindications to fNIRS, MRI, and tDCS (e.g., brain skin injury, pacemaker, metal implants in the brain),
  • neurological disorders, gait-precluding pain or comorbidity,
  • contraindications to exercise (e.g., unstable angina),
  • history of seizure or epilepsy,
  • color blindness
  • unable to walk with/without a mobility aid while responsing stimulus by the remote control

Where in Hong Kong

  • The Hong Kong Polytechnic UniversityHong Kong, Hong KongContact: Marco Yiu-Chung PangTaking people

About the trial

What the trial wants to find out

This study aims to evaluate the effects of tDCS combined with cognitive-motor training on dual-task interference during walking and foot pedaling, alongside corresponding alterations in brain activity assessed via fNIRS. Additionally, an fMRI component was conducted as a nested sub-study for deep mechanistic exploration.

The 2 groups in the trial

  • active tDCS combined with dual-task groupTreatment being tested

    patients receive three active tDCS and three dual motor-cognitive exercise training per week for four weeks.

    Treatment: active tDCS with dual-task training

  • sham tDCS combined with dual-task groupExisting treatment, for comparison

    Patients receive three sham tDCS and three dual cognitive-motor exercise training per week for four weeks.

    Treatment: sham tDCS with dual-task training

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Effect of Dual-task Training Combined With tDCS on Cognitive-motor Interference and Related Brain Activity in Stroke Patients
Plain-language title
Brain stimulation with walking and pedaling exercises for stroke patientsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
14 October 2026