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Tracking Long-Term Disabilities After Stroke in Taiwan

Follows adults with recent stroke to study disabilities such as movement, thinking, mood and seizures.

Plain-language title generated from the registry record
Registry title: Taiwan Post-Stroke Disability Study

Key facts

Where
Taipei, TaiwanSee the site

Where in Taiwan

  • National Taiwan University Hospital, Taipei,Taipei, TaiwanTaking people

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  2. Are travel costs paid?
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  4. What happens if I want to stop?
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Trial details

Who runs it
National Taiwan University Hospital
Trial code
NCT06772194
Record updated
13 May 2025
Original description
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range of disabilities in areas such as motor function, swallowing, cognition, depression, and epilepsy.Read full original descriptionShow less

Taiwan Post-Stroke Disability Study (T-PODS): A Survey of Multiple Post-Stroke Disability Domains Among Stroke Patients in Taiwan

Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range of disabilities in areas such as motor function, swallowing, cognition, depression, and epilepsy.

This study will investigate these disabilities by enrolling 2,000 acute stroke patients (both ischemic and hemorrhagic) from 10 medical centers across Taiwan. Data will be collected at three key points: at enrollment, three months, and twelve months post-stroke, using surveys, assessments, imaging, and blood samples. The aim is to examine the prevalence, risk factors, and long-term changes of post-stroke disabilities, ultimately seeking ways to reduce the health burden of stroke in Taiwan.

Inclusion: Ischemic stroke confirmed by MRI, or hemorrhagic stroke diagnosed by CT or MRI; Age ≥ 18 years; Pre-stroke modified Rankin Scale (mRS) score of 0, 1, or 2; Post-stroke mRS score of 0, 1, 2, 3, or 4 at enrollment; Able to undergo cognitive function screening and other scale assessments within 30 days post-stroke.

Exclusion: History of clinical stroke within three months prior to enrollment; Severe dementia prior to the stroke; Transient ischemic stroke and subarachnoid hemorrhage; Clear and severe psychiatric or emotional disorders before the stroke, including schizophrenia, major depressive disorder, and bipolar disorder; Pre-stroke modified Rankin Scale (mRS) score ≥ 3; Post-stroke mRS score of 5 at enrollment; History of cancer with an expected life expectancy of less than one year; Expected life expectancy of less than one year due to other medical conditions; Unable to communicate or cooperate for assessments due to severe aphasia; Anticipated inability to complete a one-year follow-up; Other situations deemed unsuitable for enrollment by the clinical investigator.

ClinicalTrials.gov NCT06772194