Testing 3D-printed resorbable scaffolds for jaw bone regeneration in adults
Tests a 3D-printed plastic scaffold to help regrow jaw bone in adults.
Plain-language title generated from the registry record
Registry title: Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
Key facts
- Where
- Valdivia, ChileSee the site
- Phase
- Phase 3
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 30 to 70 in Valdivia, Chile, who need bone rebuilt in the jaw before dental implants.
- Age
- 30 to 70 years
- Sex
- All sexes can join.
- Disease stage
- Thin (atrophic) lower jaw on both sides with little bone, behind tooth #3.3 or #4.3. The toothless ridge has 6 mm or less of bone height.
- Earlier treatment
- People who had earlier dental implant surgery cannot join.
Main reasons for not taking part
- Earlier dental implant surgery
- Sinus problems or lesions of the mouth tissue
- Smoking more than 5 cigarettes a day
- Taking any antiplatelet or anticoagulant drug
- Poorly controlled diabetes, heart disease, or a health condition that rules out surgery
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 70 years old?
Source: NCT06773923, who can take part
Where in Chile
- ValdiviaValdivia, ChileNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Universidad Austral de Chile
- Trial code
- NCT06773923
- Record updated
- 15 January 2025
- Original description
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or mandible of elderly patients in the city of Valdivia between the years 2023-2024.Read full original descriptionShow less
Effectiveness of Patient-specific 3D-printed Resorbable Scaffolds of Polycaprolactone, Beta-tricalcium Phosphate, and Metformin Used for Maxillary Bone Regeneration: Randomized Clinical Trial
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or mandible of elderly patients in the city of Valdivia between the years 2023-2024.
The main beneficiaries will be patients, users of the public or private health system, who require bone regeneration. The intermediate beneficiaries are the health team: doctors specializing in surgery and orthopedics, dentists, maxillofacial surgeons, dedicated to bone reconstruction and regeneration.
The innovation of this new material is based on the provision of a biocompatible plastic, easy to handle, for domestic 3D printing of bone matrices that can be grafted in areas requiring bone regeneration.
Inclusion: patients from the city of Valdivia, Chile, from Dental Health Service of the Base Hospital of Valdivia for the rehabilitation of their teeth with dental implants,; age between 30 and 70 years old,; regardless of sex,; complete medical history (such as sex, age and comorbidities) will be recorded; patients requiring bone regeneration at the time of examination should have an atrophic bilateral mandible with poor bone available according to periodontal deseases classification behind tooth #3.3 or #4.3; with an edentulous alveolar ridge with a remaining bone height of ≤ 6 mm.
Exclusion: patients had previous dental implant surgeries,; patients taking any antiplatelet or anticoagulant drug,; diseases that produce acute/chronic pain,; who suffer from any systemic disease whose surgical intervention is prohibited, for example: severe heart disease, congenital coagulation factor deficiency, dialysis, or malignant tumor in terminal phase,; patients with a history of heart disease; patients with diabetes that is not well controlled or who have difficulty achieving an Hb ≥ 7 g/dL in a preoperative examination,; with maxillary sinus pathologies or oral tissue lesions,; smokers of more than 5 cigarettes per day,; with excessive alcohol consumption (more than three times per week),.