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Mouth bacteria in people with obesity before bariatric surgery

Compares gum plaque bacteria in adults with obesity by body mass index before surgery.

Plain-language title generated from the registry record
Registry title: Periodontal Microbiota of Patients Candidates for Bariatric Surgery With Body Mass Index Greater Than 30

Key facts

Where
Toulouse, FranceSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a BMI of 30 or more who are on the list for bariatric surgery. It compares the bacteria in the gum plaque of people with obesity and morbid obesity.

Age
18 years or older
Sex
All sexes can join.
Disease stage
BMI of 30 or more. The trial compares a BMI between 30 and 35 with a BMI above 35.
Earlier treatment
Cannot have taken antibiotics, prebiotics or probiotics in the month before joining. Cannot have had oral surgery in that month.

Main reasons for not taking part

  • Alcohol use above 30g/d (men) or 20g/d (women)
  • Pregnant or breastfeeding
  • HIV, HBV, HCV or mononucleosis, or chronic kidney failure (creatinine clearance below 60ml/min)
  • No teeth at all
  • Planned oral surgery, or a health problem that rules out gum probing (high risk of infective endocarditis)

Read by machine on 12 November 2026.

Where in France

  • University Hospital of ToulouseToulouse, FranceContact: Stephanie BRAYER, Clinical Trial Assistant, master's degreeTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
University Hospital, Toulouse
Trial code
NCT06781229
Record updated
8 May 2026
Original description
The goal of this observational study is to compare the microbiological composition of the periodontal plaque of obese people undergoing bariatric surgery according to their Body Mass Index. The main question it aims to answer is:Read full original descriptionShow less

Non-interventional Study Exploring the Composition of the Periodontal Microbiota of Patients With Body Mass Index Greater Than 30 That Are Candidates for Bariatric Surgery

The goal of this observational study is to compare the microbiological composition of the periodontal plaque of obese people undergoing bariatric surgery according to their Body Mass Index. The main question it aims to answer is:

Does obese patients have different microbiote according to their obesity?

Obesity being classified in two groups :

* group "obesity" for a BMI between 30 and 35 * versus "morbid obesity" group with a BMIabove 35.

Participants who are scheduled to undergo bariatric surgery as part of their regular medical care will answer questions about their quality of life, hygiene habits, and saliva and periodontal samples will be taken.

Inclusion: BMI greater than or equal to 30; Be on the list of patients scheduled for bariatric surgery,; Be able to receive information about the study and understand the information form in order to take part in the study. This implies mastering the French language,.

Exclusion: Having taken antibiotics, prebiotics or probiotics in the month prior to inclusion (this has an influence on the composition of the patient's microbiota),; For whom oral surgery is planned (surgery for benign or malignant tumours of the maxillary and mandibular bone bases), or with a history of oral surgery in the month prior to inclusion,; At risk of infection (existence of one or more of the following known chronic infectious diseases: HIV, HBV, HCV and mononucleosis) and/or chronic renal insufficiency (creatinine clearance < 60ml/min),; Alcohol consumption >30g/d (men) or 20g/d (women),; During pregnancy or breastfeeding,; Patients with a general pathology that contraindicates the performance of diagnostic procedures such as periodontal probing (patients at high risk of infective endocarditis according to the ANSM); Totally edentulous patients.

ClinicalTrials.gov NCT06781229