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Taking people in EgyptPhase 2/3

Tests inhaled nitroglycerin in severe COPD patients in intensive care

Tests inhaled nitroglycerin to see if it helps breathing in adults with advanced COPD.

Plain-language title generated from the registry record
Registry title: "The Effect of Inhaled Nitroglycerin for COPD Patients

Key facts

Where
Haram, EgyptSee the site
Phase
Phase 2/3

Where in Egypt

  • Haram HospitalHaram, EgyptTaking people

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Trial details

Who runs it
Beni-Suef University
Trial code
NCT06785337
Record updated
23 January 2025
Original description
this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPDRead full original descriptionShow less

"The Effect of Inhaled Nitroglycerin on Improving Respiratory Failure in COPD Patients Admitted to Adult Intensive Care Unit"

this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD

Inclusion: Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure > 20 mmHg).

Exclusion: Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema; Patient with hypersensitivity to nitroglycerin; Pregnant female patients.

ClinicalTrials.gov NCT06785337