NCT06786260Not yet recruiting
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
Di-PKD: A Pilot Trial of a 12-Month Targeted Dietary Intervention on Cyst Progression in Patients With Autosomal Dominant Polycystic Kidney Disease
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in serum and urinary biomarkers, total kidney volume (TKV), and cyst progression in subjects with autosomal dominant polycystic kidney disease (ADPKD). Researchers will compare the results of subjects in the study diet (interventional) arm to the results of subjects in the regular diet (control) arm.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 10 Jan 2025
- Start date
- May 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Loma Linda University
- Diseases
- Polycystic kidney disease
- NCT number
- NCT06786260
What you commit to
- Study type: Interventional
- Planned participants: 30
- From May 2026 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of dietary non-adherence
- Comorbidities that could interfere with participation (Diabetes, Heart Failure (EF\<30%) Advanced Chronic Kidney Disease (CKD) Stage 4 and higher)
Other
- Subjects on Tolvaptan
Who the study is looking for
- Confirmed diagnosis of ADPKD
- Genetic testing confirmation of PKD1 or PKD2
- eGFR \>30mL/1.73m2
- Willingness to adhere to a preconditioning diet for 1 week and ability to complete the study
- Mayo Clinic Imaging Classification (MCIC): 1C, 1D, 1E
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Loma Linda University Health Coordinator of this site? Confirm its status | Loma Linda | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.