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Early palliative care with standard treatment for advanced lung cancer

Tests early palliative care added to standard treatment in adults with advanced lung cancer.

Plain-language title generated from the registry record
Registry title: Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-small Cell Lung Cancer Patients

Key facts

Where
Bangkok, ThailandSee the site

Where in Thailand

  • Siriraj HospitalBangkok, ThailandTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Mahidol University
Trial code
NCT06786468
Record updated
22 January 2025
Original description
Early palliative care has been shown to improve the survival of advanced lung cancer patients. However, most of the clinical studies were performed in the era when systemic treatment options for this disease were limited. Currently, many effective treatment options are available, including targeted therapy and immunotherapy. These novel agents improve the treatment outcomes while having less toxicity compared to conventional chemotherapy. Moreover, medical oncologists are now trained to provide palliative care for patients. This study was designed to demonstrate whether early palliative care provided by the palliative care specialist still improves the quality of life or survival of advanced lung cancer patients compared to standard care provided by the medical oncologist.Read full original descriptionShow less

Randomized Controlled Trial of Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-small Cell Lung Cancer Patients

Early palliative care has been shown to improve the survival of advanced lung cancer patients. However, most of the clinical studies were performed in the era when systemic treatment options for this disease were limited. Currently, many effective treatment options are available, including targeted therapy and immunotherapy. These novel agents improve the treatment outcomes while having less toxicity compared to conventional chemotherapy. Moreover, medical oncologists are now trained to provide palliative care for patients. This study was designed to demonstrate whether early palliative care provided by the palliative care specialist still improves the quality of life or survival of advanced lung cancer patients compared to standard care provided by the medical oncologist.

Inclusion: Age at least 18 years old; Pathologically confirmed advanced non-small cell lung cancer; Plan to receive systemic treatment for lung cancer within three weeks; ECOG performance status 0-2 with estimated life expectancy > 24 weeks; Having at least 4 scores according to Edmonton Symptom Assessment System (ESAS); Able to complete the questionnaires.

Exclusion: Had received systemic treatment for advanced lung cancer before.

ClinicalTrials.gov NCT06786468