Tests magnetic brain stimulation for language problems after early stroke

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had a new brain infarction (stroke) within the last 7 days and now have aphasia caused by it. It tests magnetic stimulation of the brain.

Age

18 years or older

Sex

All sexes can join

Disease stage

New brain infarction confirmed by head MR, with aphasia caused by it. In hospital for 7 days or less. Right-handed.

Main reasons for not taking part

• Aphasia not caused by brain infarction
• Brain infarction older than 7 days
• Other severe nerve disease such as epilepsy or bleeding stroke
• Metal or other implants in the body, such as a pacemaker
• Pregnancy or breastfeeding

The registry criteria, word for word

What the trial wants to find out

Stroke is currently an important cause of death and disability among adults worldwide, with acute ischemic stroke being the most common type of stroke, accounting for 69.6% -72.8% of new strokes in China. The time division of the acute phase generally refers to the onset time within 1-2 weeks. About 21-38% of stroke patients have post-stroke aphasia. Post stroke aphasia is usually an acquired language disorder caused by damage to the language functional areas of the dominant hemisphere, characterized by varying degrees of impairment in some or all language functions, including speaking, listening and understanding, paraphrasing, naming, reading, and calligraphy abilities. Rehabilitation treatment for cerebral infarction should be done early rather than late. Based on this, this study aims to explore transcranial magnetic stimulation therapy for post-stroke aphasia patients in the acute phase. By regulating the balance of cortical excitability on both sides of the healthy and affected areas, early speech function rehabilitation can be achieved, which is necessary for improving the quality of life of post-stroke aphasia patients

The 2 groups in the trial

• Test groupTreatment being tested

  Targeting the left M1 area, continuous high-frequency stimulation was performed at a frequency of 10Hz with 80-100% TEP for 5 minutes each time, twice a day for a total of 5 days

  Treatment: TMS

• Control groupSham treatment, for comparison

  Consistent with the experimental group protocol, the magnetic stimulation probe is a false stimulation probe, which only produces sound but does not actually produce stimulation

  Treatment: TMS