Tests two non-drug treatments before heart surgery for brain complication risk
Tests remote ischemic preconditioning and brain stimulation before cardiac surgery in adults.
Key facts
- Who runs it
- China National Center for Cardiovascular Diseases
- Where
- Beijing, ChinaSee the site
- Trial code
- Registry title
- Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgery: a Randomized Controlled Trial
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 10 Jun 2025
- Expected to end
- 31 Jul 2028
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- active RIPC and tDCS
- Sham (No Treatment)
- Record updated
- 6 June 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 80 who will have planned heart surgery and are at high risk of nerve and brain problems afterwards.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- Heart disease needing planned (elective) surgery. High risk of nerve and brain problems after surgery, such as a previous stroke or moderate to severe narrowing of the arteries of the head and neck.
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Age range: 18-80 years old
- Surgical patients with heart disease
- Elective surgery
- Patients identified as high-risk for postoperative neurological complications; Previous stroke history; Moderate to severe stenosis of the head and neck arteries was evaluated
- Be able to understand and comply with the requirements of clinical trial protocols, and voluntarily sign informed consent forms
Who cannot take part
- -
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Where in China
- Department of Neurology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing,Beijing, ChinaContact: Yao Feng, M.DTaking people
About the trial
What the trial wants to find out
Perioperative neurological complications in cardiovascular surgical procedures are associated with a significant risk of mortality and disability. The goal of this clinical trial is to learn if ischemic preconditioning and transcranial electrical stimulation to reduce perioperative neurological complications. It will also learn about the safety of remote ischemic preconditioning and transcranial electrical stimulation before cardiac surgery. The main questions it aims to answer are "Do remote ischemic preconditioning and transcranial electrical stimulation make good effect on perioperative neurological complications?" "Are remote ischemic preconditioning and transcranial electrical stimulation safe?" Researchers will compare remote ischemic preconditioning and transcranial electrical stimulation to traditional treatment to see if remote ischemic preconditioning and transcranial electrical stimulation work to reduce perioperative neurological complications.
Read full original descriptionShow less
Participants will:Undergo remote ischemic preconditioning and transcranial electrical stimulation or sham treatment twice every day for 3 days before surgery.
Undertake psychological assessment and clinical symptom follow-up after cardiac surgery.
The 2 groups in the trial
- active RIPC and tDCSExisting treatment, for comparison
RIPC and tDCS twice every day for 3 days before cardiac surgery
- sham RIPC and tDCSSham treatment, for comparison
Sham RIPC and tDCS twice every day for 3 days before cardiac surgery
Treatment: Sham (No Treatment)
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgry: a Randomized Controlled Trial
- Plain-language title
- Tests two non-drug treatments before heart surgery for brain complication riskGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06791551, who can take part
- Record updated
- 6 June 2025