Imaging study of brain blood flow changes in people with brain tumors
Uses brain scans to study blood flow and activity in adults with glioma.
Plain-language title generated from the registry record
Registry title: Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.
Key facts
- Where
- Brussels, BelgiumSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT06797661, who can take part
Where in Belgium
- HUB-Erasme HospitalBrussels, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Erasme University Hospital
- Trial code
- NCT06797661
- Record updated
- 14 September 2026
- Original description
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI).Read full original descriptionShow less
Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI).
Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET-FDG) This research project aims at investigating the mechanisms of NVU by using a multimodal noninvasive imaging approach in neurosurgical patients.
Inclusion: patients in the study include prior imaging showing a potentially resectable intra-cerebral mass lesion. Patient has to be included before surgery, chemotherapy and radiation.
Exclusion: previous brain surgery; Previous adverse reaction to gadovist (contrast agent); respiratory failure; Diabetes (type I and II); Asthma; Claustrophobia; Pregnancy and Breath feeding.