Under construction – not a live service
Sign in
Not yet taking people in FranceNo phase

Checking spinal artery blood vessels before surgery for neuroblastic tumors in children

Reviews medical files of patients with chest neuroblastic tumors who had surgery.

Plain-language title generated from the registry record
Registry title: Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors

Key facts

Where
Amiens, Besançon, Bordeaux, Brest, Bron, Caen, Dijon, Grenoble, Le Kremlin-Bicêtre, Lille, Limoges, Marseille, Montpellier, Nancy, Nantes, Nice, Paris, Poitiers, Reims, Rennes, Rouen, Saint-Denis, Strasbourg, Toulouse, and Tours, FranceSee the 27 sites

Where in France

  • CHU D'amiensAmiens, FranceNo longer taking part
  • CHU de BesançonBesançon, FranceNo longer taking part
  • CHU de BordeauxBordeaux, FranceNo longer taking part
  • CHU de BrestBrest, FranceNo longer taking part
  • Chu de LyonBron, FranceNo longer taking part
  • CHU de CAENCaen, FranceNo longer taking part
  • CHU de DIJONDijon, FranceNo longer taking part
  • CHU de GrenobleGrenoble, FranceNo longer taking part
  • Hopital BicetreLe Kremlin-Bicêtre, FranceNo longer taking part
  • CHU de LilleLille, FranceNo longer taking part
  • CHU de LimogesLimoges, FranceNo longer taking part
  • CHU de MarseilleMarseille, FranceNo longer taking part
  • CHU de MontpellierMontpellier, FranceNo longer taking part
  • CHU de NancyNancy, FranceNo longer taking part
  • CHU NantesNantes, FranceNo longer taking part
  • CHU NiceNice, FranceNo longer taking part
  • Hopital Necker Enfants MaladesParis, FranceNo longer taking part
  • Hopital Robert DebreParis, FranceNo longer taking part
  • Hôpital TrousseauParis, FranceNo longer taking part
  • CHU de PoitiersPoitiers, FranceNo longer taking part
  • CHU de ReimsReims, FranceNo longer taking part
  • CHU de RennesRennes, FranceNo longer taking part
  • CHU de RouenRouen, FranceNo longer taking part
  • CHU de la RéunionSaint-Denis, FranceNo longer taking part
  • CHU de StrasbourgStrasbourg, FranceNo longer taking part
  • CHU de ToulouseToulouse, FranceNo longer taking part
  • CHU de ToursTours, FranceNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Assistance Publique - Hôpitaux de Paris
Trial code
NCT06798532
Record updated
12 September 2025
Original description
Neuroblastic tumors (NBTs) develop from neural crest cells that give rise to the sympathetic nervous system. They include neuroblastomas, ganglioneuroblastomas, and ganglioneuromas. They represent approximately 10% of solid tumors in children under 15 years of age. In 15 to 20% of cases, NBTs are located in the thoracic region. These paravertebral tumors have an extracanal component and some also have an intraspinal component (dumbbell tumors) that can cause spinal cord compression. Surgery for these tumors also exposes the patient to neurological complications. In the thorax, the basi-thoracic location (T9-T12) may be particularly at risk due to the presence of the artery of Adamkiewicz (AKA), which supplies blood to the spinal cord; damage to this artery can result in spinal cord ischemia. To avoid this scenario, some teams recommend performing spinal cord arteriography to identify AKA. However, many centers do not perform arteriography and do not report more postoperative complications.Read full original descriptionShow less

Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors

Neuroblastic tumors (NBTs) develop from neural crest cells that give rise to the sympathetic nervous system. They include neuroblastomas, ganglioneuroblastomas, and ganglioneuromas. They represent approximately 10% of solid tumors in children under 15 years of age. In 15 to 20% of cases, NBTs are located in the thoracic region. These paravertebral tumors have an extracanal component and some also have an intraspinal component (dumbbell tumors) that can cause spinal cord compression. Surgery for these tumors also exposes the patient to neurological complications. In the thorax, the basi-thoracic location (T9-T12) may be particularly at risk due to the presence of the artery of Adamkiewicz (AKA), which supplies blood to the spinal cord; damage to this artery can result in spinal cord ischemia. To avoid this scenario, some teams recommend performing spinal cord arteriography to identify AKA. However, many centers do not perform arteriography and do not report more postoperative complications.

Currently, there is no consensus on the indications for performing preoperative spinal arteriography in patients undergoing surgery for basi-thoracic NBT.

This study evaluates the practice in France of preoperative arteriography to identify the AKA among patients undergoing surgery for basi-thoracic neuroblastic tumors and analyzes the incidence of postoperative neurological complications in these patients.

Inclusion: Patients undergoing surgery for a neuroblastic tumor (neuroblastoma, ganglioneuroblastoma, ganglioneuroma); Basithoracic location between T8 and L1; With or without intraspinal component; Treated in a pediatric surgery department in France; Between 2005 and 2024; Adult patients or holders of parental authority of minor patients informed and not opposed to the use of data for the study.

Exclusion: Post-operative follow-up of less than 6 months.

ClinicalTrials.gov NCT06798532