Tests magnetic brain stimulation for hard-to-treat hearing voices
Tests magnetic brain stimulation, aimed by brain scans, in people with schizophrenia hearing voices.
Plain-language title generated from the registry record
Registry title: RTMS for Refractory Auditory Hallucinations Based on Personalized Targets Using Magnetoencephalography
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 13 and 55 years old?
Source: NCT06802939, who can take part
Where in China
- Shanghai Mental Health CenterShanghai, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai Mental Health Center
- Trial code
- NCT06802939
- Record updated
- 14 February 2025
- Original description
This study is an before-after study in the same patient, which enrolled 36 psychiatric patients with refractory auditory hallucinations. The target of patient intervention relies on the results of magnetoencephalography localization. The medication and dosage remain unchanged during the intervention period. The investigators assume that the intervention targets for each auditory hallucination patient are individualized.Read full original descriptionShow less
RTMS for Refractory Auditory Hallucinations Based on Personalized Targets Using Magnetoencephalography
This study is an before-after study in the same patient, which enrolled 36 psychiatric patients with refractory auditory hallucinations. The target of patient intervention relies on the results of magnetoencephalography localization. The medication and dosage remain unchanged during the intervention period. The investigators assume that the intervention targets for each auditory hallucination patient are individualized.
Inclusion: Clinical diagnosis of schizophrenia; Must be able to right-handed; Primary school education or above; Understand and sign a written informed consent form (jointly signed by the guardian and the participant if under 18 years old); Existence of persistent auditory hallucinations (defined as: taking sufficient antipsychotic medication for at least 6 months, combined with 3 antipsychotic medications still ineffective, and no significant improvement in auditory hallucinations symptoms, with an AHRS score still>12).
Exclusion: Taboo symptoms for rTMS treatment (such as intracranial metal implants); Metal (including orthodontic treatment, dental implants) and tattoos inside the body; Major physical illnesses (organic lesions such as sensory and motor disorders, neurological disorders, and traumatic brain injury); MECT treatment within the past 3 months; Aggressive behavior and an impulse to damage equipment; Claustrophobia.