Spectral CT Scans to Look for Heart Muscle Damage in Chest Pain
Tests spectral CT heart scans in adults with acute chest pain to detect myocarditis.
Key facts
- Who runs it
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Where
- Bologna, ItalySee the site
- Trial code
- Registry title
- Role of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 18 Nov 2024
- Expected to end
- Feb 2027
- Type of study
- Observational
- Record updated
- 3 February 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with sudden chest pain who are having a heart CT scan. It uses a special CT technique to look for signs of heart muscle damage.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Sudden chest pain with a low or medium chance of coronary artery disease. The ECG and/or troponin test is unclear or abnormal.
Main reasons for not taking part
- Cannot have CT scan or iodine contrast dye (for example pregnancy)
- Severe kidney problems not on dialysis (GFR < 15-30 ml/min/1.73m2)
- CT images of too poor quality to read, for example because of movement
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Age greater than or equal to 18 years
- patients with acute chest pain and indication for triple-rule-out CT or coronary CT examination, i.e. low/intermediate probability of acute coronary artery disease, ECG and/or troponin not diagnostic or altered
- Obtaining informed consent
Who cannot take part
- Absolute contraindications to CT examination and/or iodinated mdc administration (i.e. pregnancy, severe renal impairment in non-dialysis patients with GFR < 15-30 ml/min/1.73m2 )
- CT examinations that do not allow diagnostic information to be provided because they are assessed as quality too scarce and not interpretable (affected by artifacts such as motion artifacts)
Where in Italy
- IRCCS Azienda Ospedaliero-Universitaria di BolognaBologna, ItalyContact: Vincenzo Russo, MDTaking people
About the trial
What the trial wants to find out
It is a spontaneous, observational cross-sectional and single-center imaging (CT and MRI) study, coupled with clinical-laboratory data. Patients with acute chest pain with low/intermediate probability of coronary artery disease, ECG and/or troponin not diagnostic or altered according to the current "standards of care" used in the ED/Department (ESC Guidelines 2020), will be enrolled consecutively and will undergo CT examinations by means of "Spectral" CT technology. CT investigation will allow to identify any non-myocarditis causes of acute chest pain and by means of spectral analysis of CT images it will try to identify signs suggestive of damage myocardial (such as ECV, LIE, hyperemia and edema).
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Role of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain
- Plain-language title
- Spectral CT Scans to Look for Heart Muscle Damage in Chest PainGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 3 February 2025