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Taking people in ItalyNo phase

Studies brain and nerve tests that may predict movement recovery after stroke

Checks brain scans and nerve tests in adults with stroke.

Plain-language title generated from the registry record
Registry title: Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome

Key facts

Where
Roma, ItalySee the site

Where in Italy

  • IRCCS San RaffaeleRoma, ItalyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
IRCCS San Raffaele Roma
Trial code
NCT06805929
Record updated
4 November 2026
Original description
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.Read full original descriptionShow less

Correlation Study Between Clinical, Neurophysiological, and Neuroradiological Biomarkers and Rehabilitation Outcomes to Predict Functional Recovery After Stroke and Personalize Treatment.

Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.

Inclusion: First stroke in the middle cerebral artery territory; Ischemic or hemorrhagic stroke (7-30 days post-acute event); Upper limb plegia or paresis; Both genders, aged >18 years; Ability to provide informed consent by the patient or caregiver/responsible relative.

Exclusion: Previous stroke; Stroke in territories other than the middle cerebral artery; History of cancer in the past two years; Presence of other neurological conditions interfering with biomarkers; Inability to provide informed consent; Contraindications to TMS or MRI.

ClinicalTrials.gov NCT06805929