Testing magnetic stimulation for social connection differences in teens with autism
Tests transcranial magnetic stimulation in teens with autism spectrum disorder to study brain social networks.
Plain-language title generated from the registry record
Registry title: Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities
Key facts
- Where
- Newark, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 13 and 18 years old?
Source: NCT06807684, who can take part
Where in United States
- Christiana CareNewark, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Christiana Care Health Services
- Trial code
- NCT06807684
- Record updated
- 21 February 2025
- Original description
There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting this network contribute to the core deficits in ASD.Read full original descriptionShow less
Discerning the Abnormal Functional Connectivity Involving the Social Reciprocity Network in Autism Spectrum Disorder and the Impact of Transcranial Magnetic Stimulation in Mitigating the Abnormalities
There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting this network contribute to the core deficits in ASD.
The overarching goal of this trial is to explore abnormalities involving the neuronal connectivity and oscillatory patterns within the social reciprocity network and to elucidate the role of modulating this network via rTMS in improving the above measures and social cognition in ASD. Quantitative electroencephalography (QEEG) coherence and spectral power analysis are reliable measures of neuronal connectivity and dynamics. The investigators aim to study the QEEG coherence/spectral power analysis to explore the neuronal dynamics affecting the social reciprocity network in ASD.
Inclusion: Fulfilling the DSM-V criteria for ASD and confirmed by CARS2, HF Exclusion criteria; Patients with ASD exhibiting significant anxiety or contact avoidance, precluding them from cooperating with the procedure; Patients with a known diagnosis of seizures; Presence of any metallic implants or devices in the head or neck area; Pregnant women.